Results 111 to 120 of about 17,253,331 (391)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Vaginal Fluid hCG Levels for Detecting Premature Rupture of Membranes

پزشکی بالینی ابن سینا, 2004
The aim of this study was to determine whether there is any different in hCG levels of vaginal fluids from normal pregnant women, women with confirmed PROM and with suspected PROM.
Tayebeh Artimani
doaj  

Children's rights in the digital age: a download from children around the world [PDF]

Evidence from across the world is telling us that no matter where they are from, more and more children are relying on digital tools, platforms and services to learn, engage, participate, play, innovate, work or socialise.
Amanda Third, Delphine Bellerose, Emma Keltie, Kari Pihl, Urszula Dawkins   +4 more
core  

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Does the Angulation of an Impacted Mandibular third Molar Affect the Prevalence of Preoperative Pathoses?

Journal of Dentistry, 2019
Statement of the Problem: The removal of a third molar tooth associated with a pathological condition is usually an easy decision. However, it is necessary for clinicians to know about the prevalence of preoperative pathologies associated with impacted ...
Ahmet Altan , Nihat Akbulut
doaj  

Physiological adjustments and circulating microRNA reprogramming are involved in early acclimatization to high altitude in Chinese Han males

Frontiers in Physiology, 2016
Background Altitude acclimatization is a physiological process that restores oxygen delivery to the tissues and promotes oxygen use under high altitude hypoxia. High altitude sickness occurs in individuals without acclimatization.
Bao Liu, He Huang, Shou-Xian Wang, Gang Wu, Gang Xu, Bing-Da Sun, Er-Long Zhang, Yu-Qi Gao   +7 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Time From Referral to Discharge From High Secure Care: Challenges for Flow Through the Forensic Estate

BJPsych Open
Aims The Independent Forensic Mental Health Review (Scottish Government, 2021) highlighted an issue with timely transitions through and out of Scottish forensic inpatient services.
Gavin Third, Cheryl Rees, Lindsay Thomson, Lindsay Gilling McIntosh   +3 more
doaj   +1 more source

Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs

Brazilian Journal of Medical and Biological Research, 2012
Hypoxia inducible factor-1α (HIF-1α) is an important transcription factor, which plays a critical role in the formation of solid tumor and its microenviroment.
Zeng Dong-Feng, Liu Ting, Chang Cheng, Zhang Xi, Liang Xue, Chen Xing-Hua, Kong Pei-Yan   +6 more
doaj   +1 more source

THIRD INTERNATIONAL CONGRESS OF APPLIED CHEMISTRY. [PDF]

, 1899
Charles E. Munroe
openalex   +1 more source