Results 91 to 100 of about 13,233,408 (362)

Third order differential equations with delay

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2015
In this paper, we study the oscillation and asymptotic properties of solutions of certain nonlinear third order differential equations with delay. In particular, we extend results of I.
Petr Liška
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Oscillation of solutions for third order functional dynamic equations

open access: yesElectronic Journal of Differential Equations, 2010
In this article we study the oscillation of solutions to the third order nonlinear functional dynamic equation $$ L_{3}(x(t))+sum_{i=0}^{n}p_i(t)Psi_k{alpha_ki}(x(h_i(t)))=0, $$ on an arbitrary time scale $mathbb{T}$.
Elmetwally M. Elabbasy, Taher S. Hassan
doaj  

Investigating Oscillatory Behavior in Third-Order Neutral Differential Equations with Canonical Operators

open access: yesMathematics
In this study, we aim to set new criteria regarding the asymptotic behavior of the neutral differential equation of the third order. These criteria are designed to ensure that this equation is oscillatory using comparisons with first-order differential ...
Abdulaziz Khalid Alsharidi, Ali Muhib
doaj   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Matrix Sequences of Third-Order Pell and Third-Order Pell -Lucas Numbers

open access: yes, 2020
In this paper, we define third-order Pell and third-order Pell-Lucas matrix sequences and investigate their properties.
openaire   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

open access: yesFEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko   +2 more
wiley   +1 more source

Third order optical nonlinearity of graphene

open access: yesNew Journal of Physics, 2014
We perform a perturbative calculation of the third order optical conductivities of doped graphene, using approximations valid around the Dirac points and neglecting effects due to scattering and electron–electron interactions.
J L Cheng, N Vermeulen, J E Sipe
doaj   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

open access: yesFEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Home - About - Disclaimer - Privacy