Results 81 to 90 of about 13,233,408 (362)

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

Geometrical Picture of Third-Order Tensors [PDF]

open access: yes, 2013
Because of its strong physical meaning, the decomposition of a symmetric second-order tensor into a deviatoric and a spheric part is heavily used in continuum mechanics. When considering higher-order continua, third-order tensors naturally appear in the formulation of the problem.
openaire   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Third-Order Nonlinear Semi-Canonical Functional Differential Equations: Oscillation via New Canonical Transform

open access: yesMathematics
This paper focuses on the oscillatory properties of the third-order semi-canonical nonlinear delay differential equation. By using the new canonical transform method, we transformed the studied equation into a canonical-type equation, which simplified ...
Ekambaram Chandrasekaran   +3 more
doaj   +1 more source

On Third-Order Linear Recurrent Functions [PDF]

open access: yesDiscrete Dynamics in Nature and Society, 2019
A function ψ:R→R is said to be a Tribonacci function with period p if ψ(x+3p)=ψ(x+2p)+ψ(x+p)+ψ(x), for all x∈R. In this paper, we present some properties on the Tribonacci functions with period p. We show that if ψ is a Tribonacci function with period p, then limx→∞ψ(x+p)/ψ(x)=β, where β is the root of the equation x3-x2-x-1=0 such that 1<β<2.
openaire   +2 more sources

PT -symmetric waveguide system with evidence of a third-order exceptional point [PDF]

open access: yes, 2017
CITATION: Schnabel, J., et al. 2017. PT-symmetric waveguide system with evidence of a third-order exceptional point. Physical Review A, 95(5):053868, doi:10.1103/PhysRevA.95.053868.
J. Schnabel   +4 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

The deficiency index of a third order operator [PDF]

open access: yesPacific Journal of Mathematics, 1977
Let L be a formally selfadjoint third order linear ordinary differential operator defined on [r, x). Using a method of Fedorjuk, asymptotic formulas are found for the solutions of Ly = iσy, σ^O. These formulas are used to determine the deficiency index of L when L has polynomial coefficients.
openaire   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Oscillation criteria for third-order nonlinear differential equations with functional arguments

open access: yesElectronic Journal of Differential Equations, 2013
In this article, we consider the third-order nonlinear differential equations with functional arguments. By using the Riccati inequality, we find conditions for all solutions to be oscillatory.
Yutaka Shoukaku
doaj  

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