Therapeutic efficacy of favipiravir against Bourbon virus in mice [PDF]
Bourbon virus (BRBV) is an emerging tick-borne RNA virus in the orthomyxoviridae family that was discovered in 2014. Although fatal human cases of BRBV have been described, little is known about its pathogenesis, and no antiviral therapies or vaccines ...
Bailey, Thomas +11 more
core +3 more sources
Spillover of Peste des Petits Ruminants Virus from Domestic to Wild Ruminants in the Serengeti Ecosystem, Tanzania [PDF]
We tested wildlife inhabiting areas near domestic livestock, pastures, and water sources in the Ngorongoro district in the Serengeti ecosystem of northern Tanzania and found 63% seropositivity for peste des petits ruminants virus. Sequencing of the viral
Eblate, E +9 more
core +3 more sources
Molecular Evidence of Orthomyxovirus Presence in Colombian Neotropical Bats
The Orthomyxoviridae family includes the genera Influenzavirus, Isavirus, Quaranjavirus, and Thogotovirus. In turn, Influenzavirus can be classified into four types: α, β, γ, and δ (Formerly A, B, C, and D), from which Alphainfluenzavirus (AIV) has the ...
Manuel Uribe +3 more
doaj +1 more source
Mx1 in hematopoietic cells protects against Thogoto virus infection [PDF]
Myxovirus resistance 1 (Mx1) is an interferon-induced gene that encodes a GTPase that plays an important role in the defense of mammalian cells against influenza A and other viruses.
Kochs, Georg +4 more
core +2 more sources
Synthesis of IFN-β by Virus-Infected Chicken Embryo Cells Demonstrated with Specific Antisera and a New Bioassay [PDF]
Transcripts of interferon-α(IFN-α) and IFN-β genes are present in virus-infected chicken cells, but because of a lack of appropriate assays and reagents, it was unclear if biologically active IFN-β is secreted.
Harlin, Olof +4 more
core +1 more source
Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene) [PDF]
Background Borna disease virus (BDV) is the type member of the Bornaviridae, a family of viruses that induce often fatal neurological diseases in horses, sheep and other animals, and have been proposed to have roles in certain psychiatric diseases of ...
Courtney E Garry, Robert F Garry
core +3 more sources
Comparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domains. [PDF]
Orthomyxovirus Influenza A virus (IAV) heterotrimeric polymerase performs transcription of viral mRNAs by cap-snatching, which involves generation of capped primers by host pre-mRNA binding via the PB2 subunit cap-binding site and cleavage 10-13 ...
Delphine Guilligay +7 more
doaj +1 more source
Detection of Brucella abortus DNA and RNA in different stages of development of the sucking louse Haematopinus tuberculatus [PDF]
Background: Brucellosis is considered the world’s most widespread zoonotic infection. It causes abortion and sterility in livestock leading to serious economic losses and has even more serious medical impact in humans, since it can be a trigger to more
Borriello G +8 more
core +1 more source
Humoral immune response after seasonal influenza vaccination [PDF]
Introduction: Seasonal vaccination provides short-lasting and strain specific protection. Different factors influence efficacy and effectiveness and are related to the vaccine and the receptor.
Sánchez de Prada, Laura
core +1 more source
The Ticks (Arachnida: Acari: Ixodida) of Arkansas [PDF]
Although ticks are a nuisance to humans and other animals, they are an important part of the biota of North America. In addition, they are vectors of many tick-borne disease agents that can negatively affect higher vertebrates.
Durden, L. A. +2 more
core +2 more sources

