Results 41 to 50 of about 660 (111)
Trabalho apresentado no Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH), 65th, 13 Nov. 2016.
Allen, E+12 more
openaire +12 more sources
Structural analysis of tumor‐related single amino acid mutations in human MxA protein
Abstract Background Human myxovirus resistant protein A (MxA), encoded by the myxovirus resistance 1 (Mx1) gene, is an interferon (IFN)‐triggered dynamin‐like multi‐domain GTPase involved in innate immune responses against viral infections. Recent studies suggest that MxA is associated with several human cancers and may be a tumor suppressor and a ...
Jia‐Li Hu+4 more
wiley +1 more source
Bourbon Virus in Wild and Domestic Animals, Missouri, USA, 2012–2013
Since its recent discovery, Bourbon virus has been isolated from a human and ticks. To assess exposure of potential vertebrate reservoirs, we assayed banked serum and plasma samples from wildlife and domestic animals in Missouri, USA, for Bourbon virus ...
Katelin C. Jackson+9 more
doaj +1 more source
Rapid Molecular Detection Methods for Arboviruses of Livestock of Importance to Northern Europe
Arthropod‐borne viruses (arboviruses) have been responsible for some of the most explosive epidemics of emerging infectious diseases over the past decade. Their impact on both human and livestock populations has been dramatic. The early detection either through surveillance or diagnosis of virus will be a critical feature in responding and resolving ...
Nicholas Johnson+5 more
wiley +1 more source
Soluble Host Defense Lectins in Innate Immunity to Influenza Virus
Host defenses against viral infections depend on a complex interplay of innate (nonspecific) and adaptive (specific) components. In the early stages of infection, innate mechanisms represent the main line of host defense, acting to limit the spread of virus in host tissues prior to the induction of the adaptive immune response.
Wy Ching Ng+4 more
wiley +1 more source
Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins.
Antagonistic interactions drive host-virus evolutionary arms races, which often manifest as recurrent amino acid changes (i.e., positive selection) at their protein-protein interaction interfaces.
Rossana Colón-Thillet+7 more
doaj +1 more source
Introduction. There are natural foci of Crimean-Congo hemorrhagic fever (CCHF) that vectored by Hyalomma marginatum ticks in Volga river delta (Astrakhan region, South of Russia). The circulation of Dhori virus (DHOV) (Thogotovirus: Orthomyxoviridae) has
E. V. Vakalova+7 more
doaj +1 more source
Active and passive surveillance, followed by gene sequencing, continue to be used to identify a diverse range of novel bacteria, viruses, and other microorganisms in ticks with the potential to cause disease in vertebrate hosts following tick bite.
Paul Selleck+6 more
doaj +1 more source
Objective Idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic autoimmune diseases characterized by specific clinical features and, frequently, skeletal muscle inflammation. Specific subtypes of IIMs can be characterized by myositis‐specific autoantibodies and are associated with distinct clinical phenotypes.
Sahana Jayaraman+5 more
wiley +1 more source
Baculovirus GP64 is grouped with rhabdovirus G, herpesvirus gB, and thogotovirus glycoproteins as a class III viral fusion protein. In their postfusion structures, these proteins contain five domains (domains I to V).
Qianlong Yu+5 more
semanticscholar +1 more source