Results 61 to 70 of about 461,748 (248)

MetaboSense: An Integrated Quantum Dot‐Mediated Aptamer Assay and Modular Microfluidic Platform for Continuous In‐Line Monitoring of Lung Metabolism During Ex Vivo Perfusion

Advanced Science, EarlyView.
MetaboSense is a first‐of‐its‐kind microfluidic platform enabling continuous, in‐line monitoring of glucose and lactate during ex vivo lung perfusion. Combining a quantum dot–mediated aptamer assay with mixing, depletion, and optofluidic detection modules, it achieves 60–s temporal resolution and shows strong agreement with standard blood gas analyzers,
Sanjana Srikant, Pouyan Keshavarz Motamed, Thomas Borrillo, Lielle Ronen, Gabriel Siebiger, Guillermo Garza, Hesam Abouali, Md Fahim Al Fattah, Ines Jaber, Dayan Ban, Marcelo Cypel, Mingyao Liu, Shaf Keshavjee, Andrew T. Sage, Mahla Poudineh   +14 more
wiley   +1 more source

Vascularização arterial dos lobos torácicos do timo em fetos de suínos da Linhagem C40 Arterial vascularization of the thoracic lobes of the thymus in stillborns of the lineage C40

Pesquisa Veterinária Brasileira, 2009
As origens e distribuições das artérias que vascularizaram os lobos torácicos do timo foram estudadas em fetos de 30 suínos da linhagem C40, sendo 12 machos e 18 fêmeas.
Eduardo M.M. Lima, Frederico O.C. Silva, L.S. Elton Rafael, Renato, S. Severino, Sérgio S. Drummond, Pedro P. Bombonato, Daniela M. Dianese   +6 more
doaj   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Computed Tomographic Anatomy of the Thoracic Cavity Vessels in the Rayini Goat [PDF]

Iranian Journal of Veterinary Surgery, 2012
Objectives- To provide a reference anatomy of the thoracic cavity vessels of the Rayini goat by using Computed tomography. Design- Experimented study. Animals- Five healthy Rayini goat.
Bahador Shojaei, Darioush Vosough, Farzaneh Sharifi   +2 more
doaj  

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Dupla artéria torácica esqueletizada versus convencional na revascularização do miocárdio sem CEC em diabéticos Double skeletonized internal thoracic artery vs. double conventional internal thoracic artery in diabetic patients submitted to OPCAB

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Avaliar a influência da técnica utilizada na dissecção das artérias torácicas na evolução de pacientes diabéticos submetidos a revascularização sem CEC.
Rodrigo Milani, Paulo Roberto Brofman, Maximiliano Guimarães, Laura Barboza, Rodrigo Mezzalira Tchaick, Hugo Meister Filho, Thales Baggio, Francisco Maia   +7 more
doaj   +1 more source

Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1–5: a cross-sectional study of the Copenhagen chronic kidney disease cohort

BMC Nephrology, 2020
Background Patients with chronic kidney disease (CKD) and arterial calcification are considered at increased risk of adverse cardiovascular outcomes. However, the optimal site for measurement of arterial calcification has not been determined. The primary
Ida Maria Hjelm Sørensen, Sasha Asbøll Kepler Saurbrey, Henrik Øder Hjortkjær, Philip Brainin, Nicholas Carlson, Ellen Linnea Freese Ballegaard, Anne-Lise Kamper, Christina Christoffersen, Bo Feldt-Rasmussen, Klaus Fuglsang Kofoed, Susanne Bro   +10 more
doaj   +1 more source

Detrimental effects of papaverine on the human internal thoracic artery [PDF]

, 2003
ObjectiveWe sought to determine the effects of papaverine on human and canine internal thoracic artery function and structure.MethodsVascular function was assessed with wire myography, and apoptosis was examined with confocal microscopy in arteries ...
Yang, Homer, Lee, Robert M.K.W., Teoh, Kevin, Gao, Yu-Jing   +3 more
core   +1 more source

THSD7A Exacerbates Atherosclerosis via Activation of Signaling Axis αvβ3/CEBPD/IL1A

Advanced Science, EarlyView.
THSD7A exerts pro‐inflammatory effects and exacerbates atherosclerosis. Mechanistically, THSD7A regulates endothelial cell inflammation and atherosclerosis by activating the αvβ3/CEBPD/IL1A signaling axis. THSD7A is not only a genetic marker but also a potential therapeutic target for coronary artery disease (CAD).
Jiankun Liu, Hongfei Liu, Yiqi Wan, Andong Wu, Jiayu Qiu, Xueting Gong, Ya Zhao, Yuanyuan Li, Bingbing Zhou, Yangyi Zheng, Fang Wu, Yuanzheng Zhu, Weixin Lv, Xueer Li, Qiang Yuan, Xiao‐Li Tian   +15 more
wiley   +1 more source