Results 71 to 80 of about 79,637 (312)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

Computed Tomographic Anatomy of the Thoracic Cavity Vessels in the Rayini Goat [PDF]

Iranian Journal of Veterinary Surgery, 2012
Objectives- To provide a reference anatomy of the thoracic cavity vessels of the Rayini goat by using Computed tomography. Design- Experimented study. Animals- Five healthy Rayini goat.
Bahador Shojaei, Darioush Vosough, Farzaneh Sharifi   +2 more
doaj  

Left Arterial Thoracic Outlet Syndrome [PDF]

Texas Heart Institute Journal, 2014
A 21-year-old previously healthy woman presented with left-hand pain after a fall onto outstretched hands 10 weeks earlier. On examination, her left hand was cool and pale, with absent brachial and wrist pulses. Duplex ultrasonography showed a thrombus in the left brachial artery (Fig. 1).
Tze-Woei, Tan, Raymond, Kenney, Alik, Farber   +2 more
openaire   +2 more sources

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1–5: a cross-sectional study of the Copenhagen chronic kidney disease cohort

BMC Nephrology, 2020
Background Patients with chronic kidney disease (CKD) and arterial calcification are considered at increased risk of adverse cardiovascular outcomes. However, the optimal site for measurement of arterial calcification has not been determined. The primary
Ida Maria Hjelm Sørensen, Sasha Asbøll Kepler Saurbrey, Henrik Øder Hjortkjær, Philip Brainin, Nicholas Carlson, Ellen Linnea Freese Ballegaard, Anne-Lise Kamper, Christina Christoffersen, Bo Feldt-Rasmussen, Klaus Fuglsang Kofoed, Susanne Bro   +10 more
doaj   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Contractile effects of arginine analogues on human internal thoracic and radial arteries

, 2000
Objectives: Plasma levels of endogenous guanidino-substituted analogues of L -arginine are increased in various pathologic conditions. In the present study we determined the effects of some of these compounds on basal and stimulated release of nitric ...
José María Vila, Juan Bautista Martínez-León, Salvador Lluch, Segarra, Gloria, Martínez-León, Juan Bautista, Gloria Segarra, Pascual Medina, Paloma Lluch, Lluch, Paloma, Medina, Pascual, Lluch, Salvador, Ballester, Rosa María, Vila, José María, Rosa María Ballester   +13 more
core   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Dupla artéria torácica esqueletizada versus convencional na revascularização do miocárdio sem CEC em diabéticos Double skeletonized internal thoracic artery vs. double conventional internal thoracic artery in diabetic patients submitted to OPCAB

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Avaliar a influência da técnica utilizada na dissecção das artérias torácicas na evolução de pacientes diabéticos submetidos a revascularização sem CEC.
Rodrigo Milani, Paulo Roberto Brofman, Maximiliano Guimarães, Laura Barboza, Rodrigo Mezzalira Tchaick, Hugo Meister Filho, Thales Baggio, Francisco Maia   +7 more
doaj   +1 more source

Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma

AGING MEDICINE, EarlyView.
Among 388 patients with esophageal squamous cell carcinoma who underwent curative resection, 144 (37.1%) developed lymph node metastasis. Upper thoracic tumors mainly involved upper mediastinal and upper right paratracheal nodes, whereas lower thoracic tumors more often involved paracardial and abdominal nodes.
Yuheng Wang, Qingqing Ding, Lei Xue, Jinhua Luo   +3 more
wiley   +1 more source