Results 1 to 10 of about 160,099 (251)

Pathophysiology of light phenotype SARS-CoV-2 interstitial pneumonia: from histopathological features to clinical presentations

Pulmonology, 2022
Little is known about the light phenotype of SARS-CoV-2 pneumonia, which behaves in an unusual way, unlike other known respiratory diseases. We believe that the histopathological features of early COVID-19 could be considered the pathophysiological ...
S. Oldani, C. Ravaglia, S. Bensai, L. Bertolovic, C. Ghirotti, S. Puglisi, S. Martinello, F. Sultani, C. Colinelli, S. Piciucchi, S. Simoncelli, V. Poletti   +11 more
doaj   +1 more source

A quality improvement program to reduce the time on the lung transplant waiting list at the Nantes University Hospital

Orphanet Journal of Rare Diseases, 2018
Background In 2010, the time on the lung transplant waiting list in Nantes University Hospital (NUH) was 9.2 months, compared to a French national median of about 4 months.
Isabelle Danner-Boucher, Véronique Loppinet, Aurore Boxus, Claire Dary, Anne Brigitte Lambert, Marine Prieur, Céline Vallet, Adrien Tissot   +7 more
doaj   +1 more source

Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1)

Stem Cell Research, 2022
Dyslipidemia is a key modifiable causal risk factor involved in the development of atherosclerotic cardiovascular disease. Recently, the G protein-coupled receptor 146 (GPR146), a member of the G-coupled protein receptors’ family, has been shown to be a ...
Lise Bray, Amandine Caillaud, Aurore Girardeau, Murielle Patitucci, Cédric Le May, Bertrand Cariou, Antoine Rimbert   +6 more
doaj   +1 more source

The IL-15 / sIL-15Rα complex modulates immunity without effect on asthma features in mouse

Respiratory Research, 2020
Background Interleukin 15 (IL-15) is a growth and modulating factor for B, T lymphocytes and natural killer cells (NK). Its action on innate and adaptive immunity is modulated by its alpha chain receptor (IL-15Rα).
Antoine Moui, Martin Klein, Dorian Hassoun, Eléonore Dijoux, Marie-Aude Cheminant, Antoine Magnan, Grégory Bouchaud   +6 more
doaj   +1 more source

Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia

Disease Models & Mechanisms, 2016
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a critical modulator of cholesterol homeostasis. Whereas PCSK9 gain-of-function (GOF) mutations are associated with autosomal dominant hypercholesterolemia (ADH) and premature atherosclerosis ...
Karim Si-Tayeb, Salam Idriss, Benoite Champon, Amandine Caillaud, Matthieu Pichelin, Lucie Arnaud, Patricia Lemarchand, Cédric Le May, Kazem Zibara, Bertrand Cariou   +9 more
doaj   +1 more source

Right Ventricular Strain by Magnetic Resonance Feature Tracking Is Largely Afterload-Dependent and Does Not Reflect Contractility: Validation by Combined Volumetry and Invasive Pressure Tracings

Diagnostics, 2022
Cardiac magnetic resonance (CMR) is currently the gold standard for evaluating right ventricular (RV) function, which is critical in patients with pulmonary hypertension.
Andreas Rolf, Till Keller, Jan Sebastian Wolter, Steffen Kriechbaum, Maren Weferling, Stefan Guth, Christoph Wiedenroth, Eckhard Mayer, Christian W. Hamm, Ulrich Fischer-Rasokat, Julia Treiber   +10 more
doaj   +1 more source

Robotic-Assisted Thoracic Surgery Approach to Thoracic Endometriosis Syndrome with Unilateral Diaphragmatic Palsy

Case Reports in Surgery, 2023
Endometriosis is characterized by endometrial-like glands and stroma outside the uterine cavity, affecting women of reproductive age. Thoracic endometriosis syndrome (TES) is an entity producing a range of clinical and radiological manifestations ...
Abiah Jacob, Adeyemi Coker, Steven Aleksandar Stamenkovic   +2 more
doaj   +1 more source

Familial screening in case of acute myocarditis reveals inherited arrhythmogenic left ventricular cardiomyopathies

ESC Heart Failure, 2020
Aims Several data suggest that acute myocarditis could be related to genetic variants involved in familial cardiomyopathies, particularly arrhythmogenic cardiomyopathy, but the management of patients with acute myocarditis and their families regarding ...
Nicolas Piriou, Lara Marteau, Florence Kyndt, Jean Michel Serfaty, Claire Toquet, Laurianne Le Gloan, Karine Warin‐Fresse, Damien Guijarro, Thierry Le Tourneau, Emilie Conan, Aurélie Thollet, Vincent Probst, Jean‐Noël Trochu   +12 more
doaj   +1 more source

The Morphological Transformation of the Thorax during the Eclosion of Drosophila melanogaster (Diptera: Drosophilidae)

Insects, 2023
The model organism Drosophila melanogaster, as a species of Holometabola, undergoes a series of transformations during metamorphosis. To deeply understand its development, it is crucial to study its anatomy during the key developmental stages.
Si-Pei Liu, Hao-Dong Yin, Wen-Jie Li, Zhuang-Hui Qin, Yi Yang, Zheng-Zhong Huang, Le Zong, Xiao-Kun Liu, Zhong Du, Wei-Li Fan, Ya-Qiong Zhang, Dan Zhang, Yong E. Zhang, Xing-Yue Liu, Ding Yang, Si-Qin Ge   +15 more
doaj   +1 more source

The Brugada syndrome: a rare arrhythmia disorder with complex inheritance

Frontiers in Cardiovascular Medicine, 2016
For the last ten years, applying new sequencing technologies to thousands of whole exomes has revealed the high variability of the human genome. Extreme caution should thus be taken to avoid misinterpretation when associating rare genetic variants to ...
Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Jean-Baptiste eGourraud, Julien eBarc, Julien eBarc, Julien eBarc, Aurélie eThollet, Solena eLe Scouarnec, Solena eLe Scouarnec, Solena eLe Scouarnec, Hervé eLe Marec, Hervé eLe Marec, Hervé eLe Marec, Hervé eLe Marec, Jean-Jacques eSchott, Jean-Jacques eSchott, Jean-Jacques eSchott, Richard eRedon, Richard eRedon, Richard eRedon, Vincent eProbst, Vincent eProbst, Vincent eProbst, Vincent eProbst   +24 more
doaj   +1 more source