Results 71 to 80 of about 7,661,261 (288)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
THE NON-LINGUISTIC CONTEXT – A BRIDGE TO LINGUISTIC ITEMS AND PHENOMENA [PDF]
Studies in Linguistics, Culture, and FLT, 2017 Each language is a complex system, which represents the world in a unique way, with its own stock of sounds, words, and phrases, as well as with its own grammatical constructions.
Miroslava Tsvetkova
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
, 1999 Excerpt: A behavioral technique used to help persons troubled by recurring uncontrolled thoughts and worries. Examples include obsessive rumination about cleanliness that persists even after careful washing, excessive fear of riding in automobiles or ...
Bufford, Rodger K.
core
Democracy in Islamic political thought [PDF]
, 2009 This paper surveys the growth and various phases of and influences on the concept of democracy in the Islamic political thought of the last two centuries. Among the thinkers covered in the survey are Rifa'a Tahtawi (1801-73), Khairuddin at-Tunis (1810-99)
Tamimi, Azzam S.
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
American Philosophical Quarterly, 2017 Abstract According to a criterion of difference for thoughts derived from Frege, two thoughts are different if it is at the same time possible for a rational subject to take conflicting epistemic attitudes toward them. But applying this criterion to perception-based demonstrative thoughts seems to slice thoughts too finely and lead to ...
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Counterfactual Thinking and Thought Experiments [PDF]
, 2014 As part of Timothy Williamson’s inquiry into how we gain knowledge from thought experiments he submits various ways of representing the argument underlying Gettier cases in modal and counterfactual terms.
Turkewitz, Josh
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source