Results 71 to 80 of about 3,351,684 (327)

Three Dimensional Spheroid Co-culture Invasion Assay

open access: yesBio-Protocol, 2015
The assay was developed to investigate the impact of stromal cells of different types (in our case breast cancer associated fibroblasts stably manipulated to modify expression of genes of interest) on the invasive capacity of epithelial cancer cells (in ...
Eldo Verghese, Eldo Verghese
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Single-Shot 3D Shape Reconstruction Using Structured Light and Deep Convolutional Neural Networks

open access: yesSensors, 2020
Single-shot 3D imaging and shape reconstruction has seen a surge of interest due to the ever-increasing evolution in sensing technologies. In this paper, a robust single-shot 3D shape reconstruction technique integrating the structured light technique ...
Hieu Nguyen, Yuzeng Wang, Zhaoyang Wang
doaj   +1 more source

Three-dimensional maps and subgroup growth

open access: yes, 2020
In this paper we derive a generating series for the number of cellular complexes known as pavings or three-dimensional maps, on $n$ darts, thus solving an analogue of Tutte's problem in dimension three.
Bottinelli, Rémi   +2 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Progress in three‐dimensional computed tomography reconstruction in anatomic pulmonary segmentectomy

open access: yesThoracic Cancer, 2022
The number of minimally invasive surgeries, such as video‐assisted thoracoscopic surgery and robot‐assisted thoracoscopic surgery, has increased enormously in recent years.
Zhe Wu   +3 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Three-dimensional photovoltaics [PDF]

open access: yesApplied Physics Letters, 2010
The concept of three-dimensional (3D) photovoltaics is explored computationally using a genetic algorithm to optimize the energy production in a day for arbitrarily shaped 3D solar cells confined to a given area footprint and total volume. Our simulations demonstrate that the performance of 3D photovoltaic structures scales linearly with height ...
Myers, Bryan   +2 more
openaire   +4 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Domain wall and three dimensional duality

open access: yesJournal of High Energy Physics, 2018
We discuss 1/2 BPS domain walls in the 3d N=4 $$ \mathcal{N}=4 $$ supersymmetric gauge theory which is self-dual under the 3d mirror symmetry. We find that if a BF-type coupling is introduced, invariance of the BPS domain wall under the duality ...
Minoru Eto   +2 more
doaj   +1 more source

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