Results 141 to 150 of about 12,593,924 (215)

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, Volume 13, Issue 55, 5 October 2026.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

A Pilot Study of Cardiac MRI in Breast Cancer Survivors After Cardiotoxic Chemotherapy and Three-Dimensional Conformal Radiotherapy. [PDF]

Front Oncol, 2020
Bergom C, Rubenstein J, Wilson JF, Welsh A, Ibrahim EH, Prior P, Schottstaedt AM, Eastwood D, Zhang MJ, Currey A, Puckett L, Strande JL, Bradley JA, White J.   +13 more
europepmc   +1 more source

Autoantibodies to Extracellular Erythrocyte Band 3 Epitopes Are Associated With Anemia in Plasmodium vivax Infection

American Journal of Hematology, Volume 101, Issue 10, Page 2592-2604, October 2026.
ABSTRACT Plasmodium vivax‐associated anemia is a multifactorial clinical outcome, in which the destruction of uninfected red blood cells (uRBCs) plays a major role in disease development and severity. Here, we identified autoantibody targets within the extracellular loops of Band 3 (B3), a major erythrocyte transmembrane protein.
Aline Marzano‐Miranda, Vanessa G. Fraga, Cor Jésus F. Fontes, Simone Ladeia‐Andrade, Marcelo U. Ferreira, Daniella C. Bartholomeu, Érika M. Braga   +6 more
wiley   +1 more source

A Comparative Study of the Acute Toxicities of Three-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity-Modulated Radiotherapy (IMRT) in Locally Advanced and Inoperable Oral Cavity Cancer. [PDF]

Cureus
Rahamat Ullah M, Sarkar UK, Hoque SMA, Sarker NK.   +3 more
europepmc   +1 more source

Dynamic Predictions in Non‐Small Cell Lung Cancer Using Joint Modeling of Longitudinal and Time‐To‐Event Outcomes Data

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Joint modeling (JM) of longitudinal and time‐to‐event (TTE) data is a powerful statistical technique that elucidates how temporal changes in a biomarker relate to TTE outcomes while accounting for study confounders. The growing use of next‐generation sequencing (NGS) in precision oncology, particularly in capturing circulating tumor DNA (ctDNA)
Christopher R. Pretz, Sara Wienke, Carin R. Espenschied, Samantha I. Liang, Jiemin Liao, Christopher R. Cabanski, Jim Hayes, Victoria Ngo, Enjun Yang, Amar K. Das   +9 more
wiley   +1 more source

Early outcomes of accelerated partial breast irradiation and dosimetric comparison of volumetric modulated arc therapy and three-dimensional conformal radiotherapy. [PDF]

Breast Cancer
Aoshika T, Uchida N, Tomita F, Yamauchi R, Kondo R, Kurose A, Takei J, Yoshida A, Ishikura S.   +8 more
europepmc   +1 more source

Multi‐Omics and Computational Pharmacology Approach With Experimental Validation Reveals the Antiproliferative Activity of Sophoricoside Against Pancreatic Cancer

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
An integrated pipeline combining network pharmacology, machine learning, and multi‑omics reveals that sophoricoside suppresses pancreatic cancer cell proliferation through PTPN1, a downstream effector. Elevated PTPN1 correlates with poor prognosis and immune infiltration, positioning it as a promising therapeutic node and prognostic biomarker for this ...
Peng Lin, Wei Cheng, Xin Qi, Jing Li
wiley   +1 more source

Planning-Based Dosimetric Comparison of Three-Dimensional Conformal Radiotherapy (Flattened Versus Unflattened Beams), Intensity-Modulated Radiotherapy, and Volumetric Modulated Arc Therapy for Pituitary Adenomas on Halcyon. [PDF]

Cureus
Malik D, Prasath NV, Chinnamuthu M, Mahajan R, Rajendiran G, Bagdare P.   +5 more
europepmc   +1 more source

Computational strategies to address therapeutic resistance in estrogen receptor‐positive breast cancer: A narrative review of molecular docking, molecular dynamics simulations, and emerging therapeutic targets

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Computational drug discovery integrates molecular docking, molecular dynamics simulations, and translational clinical targeting to identify next‐generation therapeutics that overcome endocrine resistance in ER‐positive breast cancer. Combined with multi‐omics, artificial intelligence, and biomarker‐guided precision oncology, these approaches accelerate
Emmanuel Ifeanyi Obeagu, Yaregal Asres
wiley   +1 more source

Dosimetric and Secondary Cancer Risk Comparison after Radiation Therapy for Breast Cancer with Three-Dimensional Conformal Radiotherapy, and Helical Tomotherapy. [PDF]

Asian Pac J Cancer Prev
Kamian S, Hashemi N, Mostaar A, Yekeh Dehghan AB, Farkhondeh F.   +4 more
europepmc   +1 more source