Results 151 to 160 of about 12,593,924 (215)

Radiation-induced acute injury of intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy in induction chemotherapy followed by concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma: a prospective cohort study. [PDF]

Sci Rep, 2021
Yao Z, Zhang B, Huang J, Shi L, Cheng B.
europepmc   +1 more source

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha, Richa Gill, Sergio Crovella, Haissam Abou‐Saleh, Sahar Isa Da'as   +4 more
wiley   +1 more source

Dosimetric and Radiobiological Comparison of Three-Dimensional Conformal Radiotherapy and Helical Tomotherapy in Whole Pelvic Radiotherapy of Prostate Cancer Patients. [PDF]

J Biomed Phys Eng
Mirzaeiyan M, Akhavan A, Amouheidari A, Adibi A, Hemati S, Etehadtavakol M, Khanahmad H, Shokrani P.   +7 more
europepmc   +1 more source

Finite Element Analysis of Upper Airway in Ansa Cervicalis Stimulation for Obstructive Sleep Apnea

The Laryngoscope, Volume 136, Issue 10, Page 4575-4584, October 2026.
We developed a subject‐specific FE model to investigate how ACS stabilizes the upper airway in OSA. Simulations demonstrate that caudal traction applied through the hyolaryngeal complex produces coordinated multilevel airway stabilization, with pronounced effects at the retropalatal and retro‐epiglottic regions under physiologic loading.
Mukund Gupta, Songrui Li, Haoxiang Luo, David T. Kent, Yike Li   +4 more
wiley   +1 more source

Evaluation of the glottic surface dose in three-dimensional conformal radiotherapy for early-stage glottic cancer using a treatment planning system. [PDF]

J Appl Clin Med Phys
Saito Y, Kanehira T, Yuki T, Myojin M.
europepmc   +1 more source

Simultaneous Measurement of In vivo and Transit Mid-Plane Doses with Ionization Chambers in Gynecological Malignancy Patients Undergoing Three-Dimensional Conformal Radiotherapy. [PDF]

J Med Phys, 2020
Kumar PS, Srinivas C, Vadhiraja BM, Banerjee S, Shreyas R, Prakash Saxena PU, Ravichandran R, Lobo D.   +7 more
europepmc   +1 more source

Posttranslational Modifications of p62/SQSTM1 in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang, Xin Jiang, Runing Qiu, Chandra Sugiarto Wijaya, Miaoqin Chen, Jin Wang, Liyuan Zhu, Hongchuan Jin, Lifeng Feng   +8 more
wiley   +1 more source

Comparative Study of Spinal Cord Toxicity from Dose Per Fraction Delivered to Cervical Spinal Cord in Head-and-neck Cancers by Volumetric-modulated Arc Therapy with Simultaneous Integrated Boost versus Three-dimensional Conformal Radiotherapy in a Murine Model. [PDF]

J Med Phys
Verma S, Gupta MK, Handu S, Rao S.
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source