Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang +9 more
wiley +1 more source
Temporal Dynamics and Heterogeneity in Brain Metastases: A Single-Center Retrospective Analysis of Vulnerabilities in Current MRI Surveillance Practices. [PDF]
Tocilă-Mătășel C, Dudea SM, Iana G.
europepmc +1 more source
Integrating Spatial Proteogenomics in Cancer Research
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
Robust 3D Multi-Object Tracking via 4D mmWave Radar-Camera Fusion and Disparity-Domain Depth Recovery. [PDF]
Xie Y +6 more
europepmc +1 more source
A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu +5 more
wiley +1 more source
Learning-Augmented MPC for Autonomous Vehicle Path Tracking via Ensemble Residual Dynamics Learning. [PDF]
Xiong L, Liu M, Xie Z, Leng B, Zhang Y.
europepmc +1 more source
Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun +5 more
wiley +1 more source
3D reconstruction and etching profile simulation for wiggling active area effect in dynamic random access memory manufacturing. [PDF]
Hu Z +16 more
europepmc +1 more source
A Diagnostic Algorithm for Reconstructing the Direction of Gunshots Using OsiriX and Maya in Living Patients: A Forensic Radiology Approach. [PDF]
Malta G +8 more
europepmc +1 more source
Global Fast Terminal Sliding Mode Control for Trajectory Tracking Control of Quadrotor UAVs. [PDF]
Gao R, Wu S, Li H.
europepmc +1 more source

