Results 111 to 120 of about 611,533 (383)

Distinct phosphorylation clusters determines the signalling outcome of the free fatty acid receptor FFA4/GPR120 [PDF]

, 2016
It is established that long-chain free fatty acids including ω-3 fatty acids mediate an array of biological responses through members of the free fatty acid receptor family, which includes FFA4.
Alvarez-Curto, Elisa, Butcher, Adrian J., Hudson, Brian D., Miller, Ashley M., Milligan, Graeme, Prihandoko, Rudi, Tobin, Andrew B., Ulven, Trond   +7 more
core   +2 more sources

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Growth performance, jejunum morphology and mucin-2 gene expression of broiler Japanese quails fed low-protein diets supplemented with threonine

Italian Journal of Animal Science, 2020
The present experiment was conducted to examine the effects of threonine supplementation in low-protein diets on growth performance, jejunum morphology, and mucin-2 gene expression in meat-type Japanese quails. A total of 800 broiler quails were assigned
Ashkan Emadinia, Majid Toghyani, Amir Davar Foroozandeh, Sayed Ali Tabeidian, Maryam Ostadsharif   +4 more
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Expression regulation of multiple key genes to improve l-threonine in Escherichia coli [PDF]

, 2020
Lei Zhao, Ying Lu, Jun Yang, Yu Fang, Lifei Zhu, Zhixiang Ding, Chenhui Wang, Wenjian Ma, Xiaoqing Hu, Xiaoyuan Wang   +9 more
openalex   +1 more source

Threonine 180 Is Required for G-protein-coupled Receptor Kinase 3- and β-Arrestin 2-mediated Desensitization of the µ-Opioid Receptor in Xenopus Oocytes [PDF]

, 2001
To determine the sites in the µ-opioid receptor (MOR) critical for agonist-dependent desensitization, we constructed and coexpressed MORs lacking potential phosphorylation sites along with G-protein activated inwardly rectifying potassium channels ...
Celvert, Jeremy P., Chavkin, Charles, Gurevich, Vsevolod V., Kovoor, Abraham, Lowe, Janet   +4 more
core  

Proteomic study of the membrane components of signalling cascades of Botrytis cinerea controlled by phosphorylation [PDF]

, 2019
Protein phosphorylation and membrane proteins play an important role in the infection of plants by phytopathogenic fungi, given their involvement in signal transduction cascades.
Amil, Francisco, Blanco-Ulate, Barbara, Cantoral Fernández, Jesús Manuel, Carrasco, Rafael, Chiva, Cristina, Escobar Niño, Almudena, Fernández Acero, Francisco Javier, Fuentes, Carlos, Lineiro, Eva, Sabido, Eduard   +9 more
core   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Characteristic Fragmentation Behavior of Linear and Cyclic O-Linked Glycopeptides and Their Peptide Skeletons in MALDI-TOF/TOF MS

Molecules
Understanding characteristic post-source decay (PSD) fragmentation patterns in tandem mass spectrometry (MS/MS) is important for the identification of target molecules.
Kohki Fukushi, Shogo Urakami, Hiroshi Hinou   +2 more
doaj   +1 more source

L-Threonine Supplementation During Colitis Onset Delays Disease Recovery

Frontiers in Physiology, 2018
Dietary nutrients have emerged as potential therapeutic adjuncts for inflammatory bowel disease (IBD) given their impact on intestinal homeostasis through the modulation of immune response, gut microbiota composition and epithelial barrier stability ...
Joana Gaifem, Joana Gaifem, Luís G. Gonçalves, Ricardo J. Dinis-Oliveira, Ricardo J. Dinis-Oliveira, Ricardo J. Dinis-Oliveira, Cristina Cunha, Cristina Cunha, Agostinho Carvalho, Agostinho Carvalho, Egídio Torrado, Egídio Torrado, Fernando Rodrigues, Fernando Rodrigues, Margarida Saraiva, Margarida Saraiva, António G. Castro, António G. Castro, Ricardo Silvestre, Ricardo Silvestre   +19 more
doaj   +1 more source