Results 131 to 140 of about 341,179 (261)

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

Angewandte Chemie, EarlyView.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan, Andrew J. Tague, Ashna A. Kumar, Marie Ranson, Christopher J. T. Hyland, Shane R. Ellis   +5 more
wiley   +2 more sources

Whole genome resequencing analysis of tobacco K326 and its cold sensitive mutant M18. [PDF]

Front Plant Sci
Yin H, Li X, Wang Y, Wang J, Deng Z, Chen Z, Tang H, Zhu L, Hu R, Hu Z.   +9 more
europepmc   +1 more source

Nuclear factor of activated T cells as a driver of tumor progression and a target for precision therapy

Animal Models and Experimental Medicine, EarlyView.
Overview illustration of dysregulated NFAT activation coordinating upstream signaling, post‐translational regulation and cancer promoting pathways to induce abnormal gene expression that drives tumor development, progression and immune escape. Abstract The Nuclear Factor of Activated T Cells (NFAT) family comprises closely related transcription factors.
Hira Khan, Khushbakhat Alia, Yusra Al Dhaheri, Muhammad Naseem, Rabah Iratni, Edgar Serfling, Khalid Muhammad   +6 more
wiley   +1 more source

Efficient production of glycine from glucose via a two-stage biosynthetic strategy. [PDF]

Microb Cell Fact
Chen L, Zheng Z, Chen F, Wang W, Huo S, Li X, Zhang A, Chen K.   +7 more
europepmc   +1 more source

Threonin [PDF]

, 2017
openaire   +2 more sources

THE THREONINE REQUIREMENT FOR GROWTH

Journal of Biological Chemistry, 1952
W C, ROSE, R E, KOEPPE, H J, SALLACH
openaire   +2 more sources

Nutrition of Threonine [PDF]

Agricultural and Biological Chemistry, 1968
YAMASHITA, Michiko, ETO, Teiichi, FUJIMAKI, Masao, SAKURAI, Yosito   +3 more
openaire   +1 more source

Single‐cell atlas of neuroglial dynamics in SNCA‐A53T Parkinson's disease mouse model

Animal Models and Experimental Medicine, EarlyView.
We performed single‐cell RNA sequencing of midbrain and striatal tissues from SNCA‐A53T Parkinson's disease (PD) mice, revealing glia‐enriched PD‐risk gene signatures and disease‐specific subpopulations. Transcriptional dysregulation of key TFs (e.g., Rorb, Foxc1) and enhanced neuroinflammatory signaling (SEMA, CCL, MIF) were identified.
Binqing Qin, Zichu Fu, Xuanxuan Zou, Senmao Chai, Jingjing Weng, Puqing Wang, Xiaodong Sun, Ming Sang   +7 more
wiley   +1 more source

The effects of valine, lysine and threonine and their optimal combinations on the synthesis of α-casein by MAC-T cells. [PDF]

Front Vet Sci
Yang M, Zhang X, Ding Y, Xie L, Gao Y, Yao K, Ren W, Yang L, Zhao Y, Shao W.   +9 more
europepmc   +1 more source