Results 141 to 150 of about 341,179 (261)

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

Investigation of potential targets and mechanisms of naringenin in the treatment of spinal cord injury: A network pharmacology, molecular docking, and molecular dynamics simulation study. [PDF]

Medicine (Baltimore)
Li AB, Sheng WB.
europepmc   +1 more source

Threonine [PDF]

, 2008
openaire   +1 more source

Nickel-Photocatalytic Deoxygenative Arylation toward β-Methyl-Branched α-Amino Acids. [PDF]

Org Lett
Stouwie B, Emmerich AR, Weyhermüller T, Beil SB.   +3 more
europepmc   +1 more source

Amino acids: Missing link in preeclampsia pathogenesis? [PDF]

Eur J Nutr
Gezer IS, Altinsoy H, Bastemur AG, Dogan O, Tanacan A, Ocal FD, Sahin D, Yazihan N.   +7 more
europepmc   +1 more source

Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium

Angewandte Chemie, EarlyView.
Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source

Inhibition of Ring-Cleaving Dioxygenases by Natural Amino Acids. [PDF]

ACS Omega
Wang Q, Li H, Gupta R.
europepmc   +1 more source

E-protein variability in Zika virus strains: A possible new O-glycosylation site and its implications. [PDF]

Indian J Med Res
Kori L, Chandra A, Mukhopadhyay L, Verma K, Gupta N.   +4 more
europepmc   +1 more source

Multi-omics integration reveals BPGM downregulation and potential plasma metabolite biomarkers for childhood asthma. [PDF]

Front Pediatr
Zhao J, Wang Z, Wang Y, Dai Q, Li M, Maimaitiniyazi A, Guo Z, Ru L.   +7 more
europepmc   +1 more source

Late‐Stage Functionalization of Peptides on the Solid Phase

Angewandte Chemie International Edition, EarlyView.
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner, Truc Lam Pham, Franziska Thomas   +2 more
wiley   +1 more source