Results 71 to 80 of about 52,600 (247)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Animals, 2021 As a consequence of the genetic selection process in growing rabbits, there are currently fast-growing animals exhibiting an average daily gain that may exceed 45 g/d.
Pablo Jesús Marín-García +6 more
doaj +1 more source
The roles of threonine deaminase in Nicotiana attenuata [PDF]
, 2006 Threonine deaminase (TD), the first enzyme to convert threonine to α-keto butyrate (α-KB) in the isoleucine (Ile) biosynthetic pathway, is up-regulated after herbivore attack and methyl jasmonate (MeJA) elicitation, and constitutively expressed in floral
Kang, J., Kang, Jin-Ho
core
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Brazilian Journal of Poultry ScienceThis study was carried out to investigate the effect of dietary L-Threonine supplementation on broiler performance, carcass characteristics, duodenal histo-morphology and litter analysis.
AA Al-Sagan, S Khalil, MP Smith
doaj +1 more source
, 2016 A, metabolic pathway of threonine breakdown to its metabolites 2-aminobutyrate, propionyl-CoA, and 2-hydroxybutyrate. Mass spectrometry-scaled intensity of threonine (B), 2-hydroxybutyrate (C), 2-aminobutyrate (D), and opthalamate (E) metabolites in the ...
Bridget M. Stroup (3190752) +5 more
core +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Is Maize Gluten a Sustainable and Effective Aquafeed Protein?
Aquaculture, Fish and FisheriesMaize gluten meal (MGM) can be considered unbalanced in its amino acid profile when used as a fishmeal replacement in aquafeeds. To address this, the present study evaluated MGM as the primary dietary protein source at two inclusion levels in common carp
Ronan Cooney +3 more
doaj +1 more source