Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin +6 more
wiley +1 more source
Exploring threshold concepts, tacit knowledge, and strategies for competency in restorative dentistry and fixed prosthodontics: a mixed-methods study among undergraduate dental students. [PDF]
Maneechot K +4 more
europepmc +1 more source
Becoming a dentist: faculty perceptions of student experiences with threshold concepts in a Canadian dental program. [PDF]
Green J, Rasmussen K.
europepmc +1 more source
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic +6 more
wiley +1 more source
How the mapping of threshold concepts across a master's programme in health professions education could support the development of mastersness. [PDF]
Archer E +3 more
europepmc +1 more source
Comparison of Different Blood Lactate Threshold Concepts for Constant Load Performance Prediction in Spinal Cord Injured Handcyclists. [PDF]
Stangier C +5 more
europepmc +1 more source
Clinical Reasoning and Threshold Concepts
Charmaine, Ma +2 more
openaire +3 more sources
Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
Identification of threshold concepts for biochemistry. [PDF]
Loertscher J +4 more
europepmc +1 more source

