Results 51 to 60 of about 918,204 (297)

The boundary flux. New perspectives for membrane process design [PDF]

, 2015
In the last decades much effort was put in understanding fouling phenomena on membranes. Many new concepts have been introduced in time, and parallel to this many parameters capable to quantify fouling issues and fouling evolution.
CHIANESE, Angelo, DE CAPRARIIS, BENEDETTA, DI PALMA, Luca, Ochando Pulido, Javier Miguel, STOLLER, Marco, VERDONE, Nicola   +5 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Quantum Error Correction and Fault-Tolerance

, 2005
I give an overview of the basic concepts behind quantum error correction and quantum fault tolerance. This includes the quantum error correction conditions, stabilizer codes, CSS codes, transversal gates, fault-tolerant error correction, and the ...
Bennett, Calderbank, Calderbank, Gottesman, Kitaev, Knill, Knill, Shor, Steane   +8 more
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Towards a TCT-inspired electronics concept inventory [PDF]

, 2014
This study reports on the initial work on the use of Threshold Concept Theory (TCT) to develop a threshold-concept inventory – a catalogue of the important concepts that underlie electronics and electrical engineering (EE) – and an assessment tool – to ...
Harlow, Ann, Peter, Mira, Scott, Jonathan B.   +2 more
core   +1 more source

Threshold concept

ASCILITE Publications, 2009
This poster proposes an approach, which uses threshold concepts as a lens through which academic developers can examine their practice in order to explain why it has been so difficult to inspire academics to adopt technologies in their teaching. Networked learning is described as a “portal” that leads to a new ontological destination and, if fully ...
openaire   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

A professional learning program for novice online teachers: Application of professional development guidelines using threshold concepts and online learning perceptions

Online Learning, 2019
The professional development of online teachers is now commonplace in most universities. Alongside the relatively straightforward decision to provide professional learning support for novice and experienced online educators within universities, decisions
Maria Northcote, Kevin P Gosselin, Peter Kilgour, Daniel Reynaud, Catherine McLoughlin   +4 more
doaj   +1 more source

Troublesome Concepts and Information Literacy: Investigating Threshold Concepts for IL Instruction [PDF]

, 2012
Librarians regularly encounter students who struggle to understand and apply information literacy concepts. A qualitative survey administered to information literacy practitioners asked about troublesome content and analyzed results using the threshold ...
Brunetti, Korey, Hofer, Amy R., Townsend, Lori   +2 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source