Results 61 to 70 of about 918,204 (297)

Generating threshold concepts for impactful learning development: exploring a new perspective on our work

Journal of Learning Development in Higher Education, 2023
Threshold concepts (TCs) represent pivotal ‘eureka’ moments in learning, where a person makes a leap in understanding or ability ‘akin to a portal, opening up a new and previously inaccessible way of thinking about something’ (Meyer and Land, 2003, p. 1)
Steven White
doaj   +1 more source

Threshold concept knowledge in analogue electronics: Support and assessment [PDF]

, 2012
In electrical engineering, as in other academic disciplines, there exist special, threshold concepts, where students often get stuck but which once grasped reveal new ways of thinking about a subject.
Harlow, Ann, Peter, Mira, Scott, Jonathan B.   +2 more
core   +1 more source

Responsible management: Engaging moral reflexive practice through threshold concepts [PDF]

, 2013
YesIn this conceptual paper we argue that, to date, principles of responsible management have not impacted practice as anticipated because of a disconnect between knowledge and practice.
A Bleakley, A Cunliffe, A Cunliffe, A Giddens, A Sinclair, A Wilson, AB Carroll, AL Cunliffe, AL Cunliffe, AL Cunliffe, Ann Cunliffe, B Gunia, C Elliot, C Hardy, C Taylor, D Blackman, D Lange, D Perkins, D Perkins, D Perkins, E Bell, E Ellsworth, E Hartman, G Cousins, G Doane, H Garfinkel, J Gooty, J Mezirow, J Shotter, J Shotter, J Yip, JA Petrick, JE Champoux, JHF Meyer, JHF Meyer, JHF Meyer, JHF Meyer, JHF Meyer, JM Alcaraz, JP Doh, JT Ziegenfuss Jr, K Mack, K Malkki, K Myers, KH Garrety, KL Ashcraft, M Adams, M Adams, M Archer, M Arvay, M Easterby-Smith, M Painter-Morland, N Adler, NM Pless, NM Pless, P Hibbert, Paul Hibbert, R Giacalone, R McCormick, R Vince, S Segal, T Maak, TT Baldwin, V Trafford, Y Gabriel   +64 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Threshold Concepts in deutschen Bibliotheken - eine Utopie?

o-bib. Das offene Bibliotheksjournal, 2017
Dieser Artikel versucht sich an einer Bestandsaufnahme der Situation in der Informationskompetenzvermittlung in Hochschulbibliotheken. Dabei geht es um die veränderten Bedürfnisse von Studierenden sowie deren Informationsverhalten.
Carolin Ahnert
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Triggering Engagement in SoTL through Threshold Concepts

International Journal for the Scholarship of Teaching and Learning, 2009
This essay is a reflection on the effectiveness of the idea of threshold concepts in engaging teaching staff in developing their scholarly teaching and scholarship of learning and teaching.
Jan McLean
doaj   +1 more source

Developing an Arctic Geology course: exploring the role of fieldwork in a challenging learning space

Uniped, 2021
This article explores how students are positioned to participate in an Arctic Geology course, what challenges students meet and how developing the course might mitigate these.
Rie Hjørnegaard Malm, Lena Håkansson
doaj   +1 more source

Computing the Least-core and Nucleolus for Threshold Cardinality Matching Games

, 2014
Cooperative games provide a framework for fair and stable profit allocation in multi-agent systems. \emph{Core}, \emph{least-core} and \emph{nucleolus} are such solution concepts that characterize stability of cooperation.
D. Schmeidler, N. Megiddo, P. Biró, W. Kern, X. Deng, X. Deng   +5 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source