Results 101 to 110 of about 12,065,388 (305)
Comparison of four threshold denoising effect curves.
, 2023 Comparison of four threshold denoising effect curves.
Guanjun Cai (14434056) +5 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
New Hope for the Fisher Effect? A Re-Examination Using Threshold Cointegration [PDF]
This paper reassesses the long-run relation between nominal interest rates and inflation using German data. It shows that the empirical rejection of the strict Fisher effect in previous studies, i.e., the finding of interest rates not fully adjusting to ...
Jens Weidmann
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Evidence That There are Threshold Effects in Risk of Radiation. [PDF]
Journal of Nuclear Science and Technology, 1998 This review provides evidence that thresholds are observd in atomic bomb survivors for teratogenic and genetic effects of radiation and that for rodents subjected to radon gas and tritiated drinking water, radiation becomes non-carcinogenic at low dose-rates.
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
AgricultureBiochar amendment holds promise for improving saline soils, yet its efficacy is often constrained by the uncertainty of application rates. In this study, a large field trial and associated statistical modeling were conducted to explore the mechanisms by ...
Tong Liu +9 more
doaj +1 more source
Effects of Parcellation and Threshold on Brain Connectivity Measures
PLOS ONE, 2019 Abstract It is shown that the statistical properties of connections between regions of the brain and their dependence on coarse-graining and thresholding in published data can be reproduced by a simple distance-based physical connectivity model.
T. C. Lacy, P. A. Robinson
openaire +4 more sources
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
LandBalancing ecological conservation with agricultural production in protected areas remains a critical challenge, particularly regarding the nexus of food, water, land, and ecosystems (FWLE).
Zheng Zuo +7 more
doaj +1 more source