Results 111 to 120 of about 3,647,403 (348)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Violation of Bell Inequalities as a Violation of Fair Sampling in Threshold Detectors
, 2009 Photomultiplier tubes and avalanche photodiodes, which are commonly used in quantum optic experiments, are sometimes referred to as threshold detectors because, in photon counting mode, they cannot discriminate the number of photoelectrons initially ...
Andrei Yu. Khrennikov +7 more
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Financial Openness, Aggregate Consumption and Threshold Effects
Pacific Economic Review, 2016 AbstractWe analyse the influence of financial openness on the level of aggregate consumption, a research question that has been left surprisingly unexplored by the previous literature. We construct a complete and balanced panel data set of 88 countries for the period 1980–2010, and then differentiate between four groups of countries.
Marwân-Al-Qays Bousmah, Daria Onori
openaire +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
EnergiesThe development of the digital economy provides important opportunities and conditions for China to achieve the goal of carbon peak and carbon neutrality.
Lingyao Wang, Taofeng Wu, Fangrong Ren
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
The impact of climate risk on renewable energy investments
Frontiers in Environmental ScienceTo address the issues of climate change, many countries are taking transitions from traditional fossil energy to renewable energy. The renewable energy enterprises are more sensitive to the impacts of policy uncertainty and weather conditions compared to
Xiaoshu Li, Zhuo Zheng, Haixia Li
doaj +1 more source