Results 131 to 140 of about 3,647,403 (348)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Cadmium in the Soil–Tea–Infusion Continuum of Selenium-Enriched Gardens: Implications for Food Safety

open access: yesFoods
Tea trees (Camellia sinensis) growing on selenium (Se)-rich soils often exhibit the phenomenon of cadmium (Cd) accumulation. However, the transport of Cd in the soil–tea tree–tea infusion continuum in such areas, as well as the impact of Se on Cd in this
Haizhong Wu   +4 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

EVIDÊNCIAS EMPÍRICAS SOBRE CONVERGÊNCIA DA DESIGUALDADE DE RENDA ENTRE OS MUNICÍPIOS CEARENSES

open access: yesRevista de Políticas Públicas, 2014
The income inequality tends to decrease in municipalities with high inequality and increase in those with low inequality? This paper intends to answer this question by checking if there was convergence of income inequality in the municipalities of the ...
Airton Lopes Amorim   +3 more
doaj  

Rapid expansion of small lakes in the permafrost zone of the Qinghai-Tibetan Plateau

open access: yesInternational Journal of Digital Earth
Understanding the dynamics of small lakes (
Tao Yin   +6 more
doaj   +1 more source

Can asymmetries account for the empirical failure of the Fisher effect in South Africa? [PDF]

open access: yes
This paper investigates whether unobserved asymmetries can account for irregularities in the Fisher effect for the exclusive case of South Africa. This objective is attained by investigating unit roots within a threshold auto-regressive (TAR) models and ...
Andrew Phiri, Peter Lusanga
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Agricultural New-Quality Productive Forces and Carbon Efficiency: Empirical Evidence from China

open access: yesAgriculture
Enhancing agricultural carbon emission efficiency (ACEE) is a pivotal pathway for advancing environmentally sustainable transformation in agriculture and achieving the ‘dual carbon’ targets.
Liudi Li   +4 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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