Results 141 to 150 of about 3,647,403 (348)

Nonlinear Driving Forces and Threshold Effects: Land Use Function Trade-Offs in the Funiu Mountain Area from a Social-Ecological System Perspective

open access: yesLand
A major obstacle to sustainable land management in ecologically sensitive areas is our limited understanding of the complex nonlinear mechanisms and threshold effects that dictate trade-offs between land use functions (LUFs).
Jie Yang   +5 more
doaj   +1 more source

The Scope of Corporate Profit Tax Consolidation: the Effect of Changing the CGT Entry Threshold [PDF]

open access: gold, 2016
A. V. Khaperskaya   +3 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Game Between Quality Induction and Traffic Constraint: A Non-Linear Threshold Study of Park Travel Carbon Emissions from an Urban–Rural Differentiation Perspective

open access: yesBuildings
As global decarbonization strategies pivot towards the burgeoning sector of recreational mobility, the tension between the attractive force of high-quality amenities and the constraining capacity of transport infrastructure in urban parks has emerged as ...
He Zhang   +5 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Overcoming the Salinity Bottleneck: Biochar-Induced Soil Organic Carbon Modulates Wheat Yield via Contrasting Pathways in a Coastal Saline Soil

open access: yesAgriculture
Biochar amendment holds promise for improving saline soils, yet its efficacy is often constrained by the uncertainty of application rates. In this study, a large field trial and associated statistical modeling were conducted to explore the mechanisms by ...
Tong Liu   +9 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Trade-Offs or Synergy? Unraveling the Coupling Mechanisms and Critical Thresholds in the Food-Water-Land-Ecosystem Nexus

open access: yesLand
Balancing ecological conservation with agricultural production in protected areas remains a critical challenge, particularly regarding the nexus of food, water, land, and ecosystems (FWLE).
Zheng Zuo   +7 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

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