Results 161 to 170 of about 3,607,125 (302)

Beyond linearity: a threshold effect links serum creatinine to SIRI in osteoporotic fractures. [PDF]

Front Med (Lausanne)
Yuan S, Lu K, Zhou XJ, Jiao HT, Guo YQ, Li C.   +5 more
europepmc   +1 more source

Threshold effect and sex characteristics of the relationship between chronic inflammation and BMI. [PDF]

BMC Endocr Disord, 2023
Liqiang S, Fang-Hui L, Minghui Q, Haichun C.   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

RP gene haploinsufficiency promotes extra sensory organ formation via a threshold effect. [PDF]

Fly (Austin)
Pi H, Chen KH, Tu H, Hsu CW.
europepmc   +1 more source

Threshold effect of technological innovation on carbon emission intensity based on multi-source heterogeneous data. [PDF]

Sci Rep, 2023
Zhao X, Xu H, Yin S, Zhou Y.
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Impact of family function on psychological distress and its threshold effect in informal caregivers of elderly people with dementia. [PDF]

BMC Nurs
Wang YX, Zhang F, Shi CQ, Shao J.
europepmc   +1 more source

A threshold effect of COVID-19 risk on oil price returns. [PDF]

Energy Econ, 2023
Sun Y, Li D, Suo C, Wang Y.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Threshold Effect of Time to Admission on Long-Term Mortality in Geriatric Hip Fractures: A 24-H Critical Window Identified. [PDF]

J Clin Med
Zhang BF, Wang MX.
europepmc   +1 more source