Results 31 to 40 of about 452,379 (303)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Burn threshold prediction for high efficiency deep grinding [PDF]
Burn threshold diagrams are useful for the prediction of thermally induced grinding damage and were originally developed to describe the conventional shallow cut grinding regime.
A. Bell +5 more
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
STUDY OF FORMALDEHYDE CONCENTRATION LEVELS IN THE AIR OF WORK PLACES
In this research, air sampling of workplaces was carried out by two methods (long - time and short - time). The mean formaldehyde concentration with long - time method in pathology labs, surgery and endoscopy sections were 0.96 0.25 and 0.13 ppm and with
M. Ghasemkhani
doaj
Rest in a Warming Workplace: Resituating the Science and Policy of Non‐Work Under Climate Change
Rest is increasingly presented as a key solution to the challenge of rising workplace temperatures under climate change. Yet, despite this growing importance, the scientific literature often treats the relationship between rest and core temperature ...
Pratik Mishra, Laurie Parsons
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Determining Free-Flow Speed on Different Classes of Rural Two-Lane Highways
Current analytical free-flow speed models consider all rural two-lane highways as the same road type despite their different functional significance in the network.
Nemanja Stepanović +2 more
doaj
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
BackgroundThe threshold limit values (TLVs) established and regularly updated by the American Conference of Governmental Industrial Hygienists (ACGIH) are widely adopted and referenced globally, serving as a crucial reference for China's occupational ...
Qiangzhi GUO +8 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

