Results 61 to 70 of about 733,905 (262)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PLoS ONE, 2019 This study aimed to investigate whether people scoring higher (compared to lower) on sensory-processing sensitivity respond differently to the work environment.
Tinne Vander Elst +5 more
doaj +1 more source
Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial. [PDF]
PLoS ONE, 2012 Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input.
Stefan A W Bouwense +5 more
doaj +1 more source
Recovery Thresholding Hyperinterpolations in Signal Processing
CoRR16 pages, 3 figures, 5 ...
Congpei An, Jia-Shu Ran
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Thresholding approach to radiography image processing acceleration [PDF]
Telfor Journal, 2017 An approach for detecting low‑value Laplacian pyramid coefficients which can be used to accelerate radiography image processing is presented.The acceleration is achieved through modifying Laplacian pyramid construction algorithm. Detection of low-value coefficients in lower pyramid layers is based on corresponding low-value higher layer coefficients ...
V. S. Ostojić +2 more
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
PROGRAM PENGHITUNG JUMLAH ORANG LEWAT MENGGUNAKAN WEBCAM
Jurnal Informatika, 2004 The amount of public places's visitor data is very important. Usually we get it manually. AT the moment, video camera has been used for security. Therefor, the people counter software has been made using Normalized Sum-squared difference (NSSD) method ...
Sudianto Lande +3 more
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source