Results 81 to 90 of about 1,964,027 (298)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
This study aimed to investigate whether people scoring higher (compared to lower) on sensory-processing sensitivity respond differently to the work environment.
Tinne Vander Elst +5 more
doaj +1 more source
Spatially Coupled Turbo Codes [PDF]
In this paper, we introduce the concept of spatially coupled turbo codes (SC-TCs), as the turbo codes counterpart of spatially coupled low-density parity-check codes. We describe spatial coupling for both Berrou et al. and Benedetto et al.
Amat, Alexandre Graell i +2 more
core +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial. [PDF]
Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input.
Stefan A W Bouwense +5 more
doaj +1 more source
Shock wave initiation of the Ti5Si3 reaction in elemental powders [PDF]
Elemental powder mixes were subjected to plane wave shock processing which reduced the initial porosity to essentially zero. Two powder mixes in a 5:3 Ti:Si atomic ratio were used: -325 mesh Ti and Si (
Montilla, K. L. +2 more
core +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Recovery Thresholding Hyperinterpolations in Signal Processing
16 pages, 3 figures, 5 ...
Congpei An, Jia-Shu Ran
openaire +2 more sources
Thresholding approach to radiography image processing acceleration [PDF]
An approach for detecting low‑value Laplacian pyramid coefficients which can be used to accelerate radiography image processing is presented.The acceleration is achieved through modifying Laplacian pyramid construction algorithm. Detection of low-value coefficients in lower pyramid layers is based on corresponding low-value higher layer coefficients ...
V. S. Ostojić +2 more
openaire +2 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source

