Results 81 to 90 of about 1,964,027 (298)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Who is more susceptible to job stressors and resources? Sensory-processing sensitivity as a personal resource and vulnerability factor.

open access: yesPLoS ONE, 2019
This study aimed to investigate whether people scoring higher (compared to lower) on sensory-processing sensitivity respond differently to the work environment.
Tinne Vander Elst   +5 more
doaj   +1 more source

Spatially Coupled Turbo Codes [PDF]

open access: yes, 2014
In this paper, we introduce the concept of spatially coupled turbo codes (SC-TCs), as the turbo codes counterpart of spatially coupled low-density parity-check codes. We describe spatial coupling for both Berrou et al. and Benedetto et al.
Amat, Alexandre Graell i   +2 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial. [PDF]

open access: yesPLoS ONE, 2012
Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disease changes in central pain processing, e.g. central sensitization manifest as spreading hyperalgesia, can result from ongoing nociceptive input.
Stefan A W Bouwense   +5 more
doaj   +1 more source

Shock wave initiation of the Ti5Si3 reaction in elemental powders [PDF]

open access: yes, 1997
Elemental powder mixes were subjected to plane wave shock processing which reduced the initial porosity to essentially zero. Two powder mixes in a 5:3 Ti:Si atomic ratio were used: -325 mesh Ti and Si (
Montilla, K. L.   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Recovery Thresholding Hyperinterpolations in Signal Processing

open access: yesCoRR
16 pages, 3 figures, 5 ...
Congpei An, Jia-Shu Ran
openaire   +2 more sources

Thresholding approach to radiography image processing acceleration [PDF]

open access: yesTelfor Journal, 2017
An approach for detecting low‑value Laplacian pyramid coefficients which can be used to accelerate radiography image processing is presented.The acceleration is achieved through modifying Laplacian pyramid construction algorithm. Detection of low-value coefficients in lower pyramid layers is based on corresponding low-value higher layer coefficients ...
V. S. Ostojić   +2 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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