Results 51 to 60 of about 256,005 (297)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Hybrid threshold adaptable quantum secret sharing scheme with reverse Huffman-Fibonacci-tree coding

open access: yes, 2016
With prevalent attacks in communication, sharing a secret between communicating parties is an ongoing challenge. Moreover, it is important to integrate quantum solutions with classical secret sharing schemes with low computational cost for the real world
Orgun, Mehmet A.   +6 more
core   +1 more source

Remark on the Threshold RSA Signature Scheme [PDF]

open access: yes, 2007
Shared generation of secure signatures, called the threshold signatures, was introduced by Desmedt and Frankel in 1991. A threshold signature scheme is not only a threshold scheme, but also a signature scheme. Therefore, it should possess the properties of both threshold scheme and digital signature scheme.
Chuan-Ming Li   +2 more
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

On threshold signcryption scheme and threshold proxy signcryption scheme with non-repudiation. [PDF]

open access: yes, 2002
by Wah-Kit Chan.Thesis (M.Phil.)--Chinese University of Hong Kong, 2002.Includes bibliographical references (leaves 84-87).Abstracts in English and Chinese.Acknowledgement --- p.iAbstract of thesis entitled: --- p.ii摘要 --- p.iiiList of Tables --- p ...

core  

A Robust Image Watermarking Technique With an Optimal DCT-Psychovisual Threshold

open access: yesIEEE Access, 2018
This paper presents a reliable digital watermarking technique that provides high imperceptibility and robustness for copyright protection using an optimal discrete cosine transform (DCT) psychovisual threshold.
Ferda Ernawan, Muhammad Nomani Kabir
doaj   +1 more source

Broadcast Enforced Threshold Schemes with Disenrollment [PDF]

open access: yes, 2004
Blakley, Blakley, Chan and Massey conjectured a lower bound on the entropy of broadcast messages in threshold schemes with disenrollment. In an effort to examine the conjecture, we identify their original scheme definition has a limitation: a coalition of participants can reconstruct all shared secrets without broadcast from the dealer, and hence ...
Mingyan Li, Radha Poovendran
openaire   +1 more source

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