Results 71 to 80 of about 256,005 (297)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A Novel Efficient (t,n) Threshold Proxy Signature Scheme

open access: yes, 2009
[[abstract]]All previously proposed threshold proxy signature schemes have been based on discrete logarithms required for a protocol to generate and verify a shared secret among the proxy group. Therefore, it is necessary for the proxy signers to perform
Huang, H. F. ; Chang, C. C.
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A Nonrepudiable Threshold Multi-Proxy Multi-Signature Scheme with Shared Verification

open access: yes, 2009
[[abstract]]In this paper, we shall propose a threshold multi-proxy multi-signature scheme with shared verification. In the scheme allows the group of original signers to delegate the signing capability to the designated group of proxy signers ...
Shiang-Feng Tzeng;Cheng-Ying Yang; Min-Shiang Hwang
core  

On QSAR-based cardiotoxicity modeling with the expressiveness-enhanced graph learning model and dual-threshold scheme. [PDF]

open access: yesFront Physiol, 2023
Wang H   +7 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

A Security Enhanced Generalized Threshold Signcryption Scheme with Deceit Detection

open access: yes工程科学与技术, 2010
:By analyzing the first generalized threshold signcryption scheme (WCL scheme) and its improved schemes (TJC scheme, etc.), it was found that they can’t resist several attacks such as equation attack and can’t realize threshold designcryption.
Zhang Wenfang, wang Xiaomin, He Dake
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Multi-policy Threshold Signature Scheme with Traceable Participant Cosigners

open access: yes, 2009
[[abstract]]In a (t, n) threshold scheme, the secret can be reconstructed by the cooperation of t or more users. With this basic concept, Lee devised a threshold signature scheme with multiple signing policies in 2001.
Chu, C. H.;Lin, H. F.;Chang, C. C.;Chen, C. Y.
core  

ID-based on-line/off-line threshold signature scheme without bilinear pairing

open access: yesTongxin xuebao, 2013
Based on the distributed key generation (DKG) protocol and verifiable secret sharing (VSS) protocol,an identity-based on-line/off-line threshold signature scheme was proposed in order to eliminate the cost of the certificate management in the public key ...
Xiao-dong YANG   +3 more
doaj   +2 more sources

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