Results 81 to 90 of about 1,111,411 (282)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

ID-based on-line/off-line threshold signature scheme without bilinear pairing

Tongxin xuebao, 2013
Based on the distributed key generation (DKG) protocol and verifiable secret sharing (VSS) protocol,an identity-based on-line/off-line threshold signature scheme was proposed in order to eliminate the cost of the certificate management in the public key ...
Xiao-dong YANG, Chun-mei LI, Ting XU, Cai-fen WANG   +3 more
doaj   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Dynamic-FROST: Schnorr threshold signatures with a flexible committee

Journal of Mathematical Cryptology
Threshold signatures enable any subgroup of predefined cardinality tt out of a committee of nn participants to generate a valid, aggregated signature.
Cimatti Annalisa, De Sclavis Francesco, Galano Giuseppe, Giammusso Sara, Iezzi Michela, Muci Antonio, Nardelli Matteo, Pedicini Marco   +7 more
doaj   +1 more source

On QSAR-based cardiotoxicity modeling with the expressiveness-enhanced graph learning model and dual-threshold scheme. [PDF]

Front Physiol, 2023
Wang H, Zhu G, Izu LT, Chen-Izu Y, Ono N, Altaf-Ul-Amin MD, Kanaya S, Huang M.   +7 more
europepmc   +1 more source

An Approximate KAM-Renormalization-Group Scheme for Hamiltonian Systems

, 1998
We construct an approximate renormalization scheme for Hamiltonian systems with two degrees of freedom. This scheme is a combination of Kolmogorov-Arnold-Moser (KAM) theory and renormalization-group techniques.
Benfatto, G., Chandre, C., Jauslin, H. R.   +2 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Node synchronization of viterbi decoders using state metrics [PDF]

The concept of node synchronization using state metrics is investigated. The branch metrics are integrated over a fixed time interval and the results are compared to the detection threshold.
Cheng, U.
core   +1 more source

Threshold Signature Schemes Application

Безопасность информационных технологий, 2015
This work is devoted to an investigation of threshold signature schemes. The systematization of the threshold signature schemes was done, cryptographic constructions based on interpolation Lagrange polynomial, elliptic curves and bilinear pairings were examined. Different methods of generation and verification of threshold signatures were explored, the
Anastasiya Victorovna Beresneva, Anna Vasilievna Epishkina   +1 more
openaire   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source