Results 101 to 110 of about 2,212,547 (297)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

The entry price threshold in EU F&V sector: deterrence or effective barrier? [PDF]

open access: yes
The paper investigates the effects of the entry price scheme for fresh fruit and vegetables. The analysis is conducted on the EU prices of tomatoes, lemons and apples for some of the main competing countries on the EU domestic markets: Morocco, Argentina,
Santeramo, Fabio G., Cioffi, Antonio
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Expenditure review of the Dental Treatment Services Scheme (DTSS) [PDF]

open access: yes, 1999
Adults on low incomes have been entitled to free dental care under health care legislation since 1953 under the Health Act. A series of policy documents advocated the implementation of adequate dental services to this group but competing forces for ...
Department of Health. Dental Treatment Services Scheme.
core  

Selection combining for noncoherent decode-and-forward relay networks

open access: yesEURASIP Journal on Wireless Communications and Networking, 2011
This paper studies a new decode-and-forward relaying scheme for a cooperative wireless network composed of one source, K relays, and one destination and with binary frequency-shift keying modulation.
Nguyen Ha, Nguyen Ha
doaj  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Migrants and poverty in the private rented sector in Dublin City: an analysis of the experience of migrants seeking assistance from Threshold [PDF]

open access: yes, 2010
This report examines the experiences of migrants in the private rented sector (PRS) in Dublin in relation to issues such as access and affordability, living conditions and landlord-tenant relations.
Threshold
core  

Security of Wang-Li Threshold Signature Scheme [PDF]

open access: yes, 2004
In 2003, Wang et al.[1] proposed a (t, n) threshold signature scheme without a trusted party based on the discrete logarithm problem. In this paper, according to [5]'s attacking method, we show that there are still some security leaks in that scheme,
Lifeng Guo
core   +1 more source

Adaptively secure, splittable, and robust threshold unsigncryption

open access: yesCybersecurity
As a variant of the signcryption scheme, threshold unsigncryption operates among multiple receiver members through a (t, n) threshold process during the unsigncryption phase to improve security and robustness, and has been widely deployed in various ...
Yuxin Tong   +4 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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