Results 121 to 130 of about 2,212,547 (297)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

A Dynamic Threshold Decryption Scheme Using Bilinear Pairings

open access: yes, 2020
A dynamic threshold sharing scheme is one that allows the set of participants to expand and contract. In this work we discuss dynamic threshold decryption schemes using bilinear pairing.
Brian King
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

On threshold signcryption scheme and threshold proxy signcryption scheme with non-repudiation. [PDF]

open access: yes, 2002
by Wah-Kit Chan.Thesis (M.Phil.)--Chinese University of Hong Kong, 2002.Includes bibliographical references (leaves 84-87).Abstracts in English and Chinese.Acknowledgement --- p.iAbstract of thesis entitled: --- p.ii摘要 --- p.iiiList of Tables --- p ...

core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

A Threshold Signature Scheme Withstanding the Conspiracy Attack

open access: yes, 2012
[[abstract]]A threshold signature, first proposed by Desmedt and Frankel, allows or more members of the group cooperate to generate a signature on behalf of the group while providing the anonymity of the signers.
Jan, Jinn-Ke; Tseng, Yuh-Min; Chien, Hung-Yu
core  

A (<i>t, n</i>) Threshold Signature Scheme Based on Factorial Decompose Theorem of Polynomial

open access: yes, 2011
The traditional threshold signature scheme is a combination of the digital signature scheme and the secret sharing scheme. Any group of t (threshold value) or more players can reconstruct the secret together but no group of fewer than t players can in ...
Yong Quan Cai, Fu Lai Cheng
core   +1 more source

A Dynamic Threshold Decryption Scheme Using Bilinear Pairings

open access: yes, 2015
A dynamic threshold sharing scheme is one that allows the set of participants to expand and contract. In this work we discuss dynamic threshold decryption schemes using bilinear pairing.
King, Brian
core   +1 more source

Dual-proxy key-based threshold signature scheme for ship ad-hoc network

open access: yesTongxin xuebao, 2018
In order to solve the problem of message authentication under the conditions of the ship ad-hoc network (SANET),a signature scheme that does not depend on trusted certificate authorities and tamper-proof devices (TPD) was proposed by using the threshold ...
Ming XU, Xuru LI, Chaobin LIU, Yao MA
doaj   +2 more sources

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