Results 101 to 110 of about 1,711,818 (299)

MOS transistor threshold voltage generator

, 1996
A threshold voltage generator for a field-effect transistor, being of a type adapted to compensate for variations of the threshold voltage from a nominal value, comprising a first amplifier having a first input connected to a current generator; a second ...
BASCHIROTTO, ANDREA, R. Alini, CASTELLO, RINALDO, S. Portaluri   +3 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Analysis of Resistive Bridge Defect Delay Behavior in the Presence of Process Variation

Recent research has shown that tests generated without taking process variation into account may lead to loss of test quality. Using transition delay test, this paper analyzes the behavior of resistive bridge defect under the influence of process ...
Reddy, Sudhakar, Khursheed, Saqib, Zhong, Shida, Chakrabarty, Krishnendu, Al-Hashimi, Bashir   +4 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Threshold Voltage Mismatch of FD-SOI MOSFETs [PDF]

The threshold voltage mismatch of FD (Fully depleted) SOI (Silicon on insulator) devices have been studied. Floating body MOSFETs operating at high drain voltage show a large mismatch in the threshold voltage compared with body-tied MOSFETs.
Taniguchi, Kenji, Matsuoka, Toshimasa, Shimizu, Yoshiyuki   +2 more
core   +1 more source

The relative voltage index: a novel tailored method to identify left atrial low voltage areas in non-paroxysmal AF

Frontiers in Cardiovascular Medicine
BackgroundThe optimal voltage threshold for determining low voltage areas (LVA) in non-paroxysmal atrial fibrillation (NPAF) is unclear. This study aims to evaluate a patient-specific voltage measurement using the left atrial appendage (LAA) as a ...
Guoshu Yang, Shiqiang Xiong, Yan Luo, Duan Luo, Michael Shehata, Zhen Zhang, Lin Cai, Xunzhang Wang, Ashkan Ehdaie, Hanxiong Liu   +9 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A Detection Method for Virtual Threshold of Busbar Voltage in Distribution Network with Distributed Wind Turbines under Reactive-Power Disturbance

Kongzhi Yu Xinxi Jishu
Distributed wind turbines are connected to nearby distribution networks through collecting circuits and variations in their output power directly impact the network voltage, subsequently affecting the operation of loads connected to the same distribution
TANG Jianping, QU Sheng, LI Yangtao, PANG Jiameng   +3 more
doaj  

Threshold voltage roll-off for sub-10 nm asymmetric double gate MOSFET [PDF]

, 2019
Threshold voltage roll-off is analyzed for sub-10 nm asymmetric double gate (DG) MOSFET. Even asymmetric DGMOSFET will increase threshold voltage roll-off in sub-10 nm channel length because of short channel effects due to the increase of tunneling ...
Jung, Hakkee
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source