Results 151 to 160 of about 274,981 (298)

Modelling reliable metabolic phenotypes by analysing the context-specific transcriptomics data. [PDF]

NPJ Syst Biol Appl
Kumar S P, Bhatt NP.
europepmc   +1 more source

Engineering Exact Quasi-Threshold Editing

, 2020
Lars Gottesbüren, Michael Hamann, Philipp Schoch, Ben Strasser, Dorothea Wagner, Sven Zühlsdorf   +5 more
openalex   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Adaptive Dynamic Thresholds for Unsupervised Joint Anomaly Detection and Trend Prediction. [PDF]

Sensors (Basel)
Ding F, Zhao Y, Li Z, Tang H, Liu Y, Guo D.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Vibration Signal Denoising Method Based on ICFO-SVMD and Improved Wavelet Thresholding. [PDF]

Sensors (Basel)
Cui Y, He X, Wu Z, Zhang Q, Cao Y.
europepmc   +1 more source

Health impact, budget impact, and price threshold for cost-effectiveness of lenacapavir for HIV pre-exposure prophylaxis in eastern and southern Africa: a modelling analysis

Linxuan Wu, David Kaftan, Rachel Wittenauer, Cory Arrouzet, Nishali Patel, Arden L. Saravis, Brian Pfau, Edinah Mudimu, Anna Bershteyn, Monisha Sharma   +9 more
openalex   +1 more source

Sustained focal cortical compression reduces electrically-induced seizure threshold

, 2008
Ming-Chieh Ding, Eng H. Lo, Garrett B. Stanley   +2 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

OPERA net Otsu driven performance enhanced image restoration algorithm. [PDF]

Sci Rep
Sharma P, Jarial P, Singla BS.
europepmc   +1 more source