Results 71 to 80 of about 274,981 (298)

Influence of Polymer Processing on the Double Electrical Percolation Threshold in PLA/PCL/GNP Nanocomposites [PDF]

, 2022
Nour-Alhoda Masarra, Jean-Christophe Quantin, Marcos Batistella, Roland El Hage, Monica Francesca Pucci, José‐Marie Lopez‐Cuesta   +5 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

THORS: An Efficient Approach for Making Classifiers Cost-Sensitive

IEEE Access, 2019
In this paper, we propose an effective THresholding method based on the Order Statistic, called THORS, to convert an arbitrary scoring-type classifier, which can induce a continuous cumulative distribution function of the score, into a cost-sensitive one.
Ye Tian, Weiping Zhang
doaj   +1 more source

Threshold Cascade Dynamics in Coevolving Networks [PDF]

, 2023
Byungjoon Min, M. San Miguel
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Cross-calibration of multiple optical instruments for the measurement of particle size distributions in water

Frontiers in Marine Science
Particle size spectra, describing particle abundance as a function of size, are essential for understanding marine ecosystem structure and biogeochemical processes. The slopes of size spectra provide insights into ecosystem characteristics.
Marika Takeuchi, Zonghua Liu, Zonghua Liu, Will Major, Yéssica Vanessa Contreras-Pacheco, Thangavel Thevar, Jack Rees Williams, Sarah Lou Carolin Giering   +7 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A Comparative Study of Image Processing Techniques for Javanese Ancient Manuscripts Enhancement

IEEE Access
Digital preservation to preserve information in ancient manuscripts is often not optimal because of the object’s condition, which has degraded over time.
Imam Yuadi, Novanto Yudistira, Habiddin Habiddin, Khoirun Nisa'   +3 more
doaj   +1 more source

Thresholds [PDF]

British Journal of General Practice, 2021
openaire   +2 more sources