Results 81 to 90 of about 1,445,591 (343)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

A novel thresholding based algorithm for detection of vertical root fracture in nonendodontically treated premolar teeth

open access: yesJournal of Medical Signals and Sensors, 2016
In this paper, an efficient algorithm is proposed for detection of vertical root fractures (VRFs) in periapical (PA), and cone-beam computed tomography (CBCT) radiographs of nonendodontically treated premolar teeth.
Masume Johari   +4 more
doaj  

An Embedded Application for Degraded Text Recognition

open access: yesEURASIP Journal on Advances in Signal Processing, 2005
This paper describes a mobile device which tries to give the blind or visually impaired access to text information. Three key technologies are required for this system: text detection, optical character recognition, and speech synthesis. Blind users and
Thillou Céline   +2 more
doaj   +1 more source

Novel Approach to Unsupervised Change Detection Based on a Robust Semi-Supervised FCM Clustering Algorithm

open access: yesRemote Sensing, 2016
This study presents a novel approach for unsupervised change detection in multitemporal remotely sensed images. This method addresses the problem of the analysis of the difference image by proposing a novel and robust semi-supervised fuzzy C-means (RSFCM)
Pan Shao   +4 more
doaj   +1 more source

Threshold hypergraphs

open access: yesDiscrete Mathematics, 1985
Threshold graphs were introduced by \textit{V. Chvátal} and \textit{P. L. Hammer} [Ann. Discrete Math. 1, 145-162 (1977; Zbl 0384.90091)]. They gave three equivalent characterizations of these graphs. These characterizations were generalized for hypergraphs by \textit{M. Ch. Golumbic} [Combinatorics, Keszthely 1976, Colloq. Math.
Reiterman, Jan   +3 more
openaire   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Effects of the Ground Resolution and Thresholding on Crack Width Measurements

open access: yesSensors, 2018
When diagnosing the condition of a structure, it is necessary to measure the widths of any existing cracks in the structure. To ensure safety when relying on images of cracks, the selected imaging parameters and processing technology must be well ...
Hyunwoo Cho   +2 more
doaj   +1 more source

Presidential Threshold Between the Threshold of Candidacy and Threshold of Electability [PDF]

open access: yesJURNAL CITA HUKUM, 2018
Abstract. In judicial review on Article 9 of Law Number 42 of 2008 on The Election of President and Vice-President which regulates Presidential threshold, the Constitutional Court refused on the grounds that it is an open legal policy which mandated by Article 6 paragraph (5) of the 1945 Constitution that the administration of the election of President
openaire   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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