Results 131 to 140 of about 308,830 (401)

Thrombin Production and Human Neutrophil Elastase Sequestration by Modified Cellulosic Dressings and Their Electrokinetic Analysis

open access: yesJournal of Functional Biomaterials, 2011
Wound healing is a complex series of biochemical and cellular events. Optimally, functional material design addresses the overlapping acute and inflammatory stages of wound healing based on molecular, cellular, and bio-compatibility issues. In this paper
Nicolette Prevost   +1 more
doaj   +1 more source

Thrombin generation in a woman with heterozygous factor V Leiden and combined oral contraceptives: A case report

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2020
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten   +3 more
doaj   +1 more source

Participation of the hypophyseal-adrenal cortex system in thrombin clearance during immobilization stress [PDF]

open access: yes
Thrombin marked with I-131 resulted in a considerable increase of the thrombined clearance rate in healthy male rats during stress caused by an immobilization lasting 30 minutes, and in an increase of thrombin clearance occurred by a combination of ...
Bazazyan, G. G.   +3 more
core   +1 more source

A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. [PDF]

open access: yes, 1985
We have previously characterized a monoclonal antibody, S12, that binds only to activated platelets (McEver, R.P., and M.N. Martin, 1984, J. Biol. Chem., 259:9799-9804). It identifies a platelet membrane protein of Mr 140,000, which we have designated as
Bainton, DF   +4 more
core   +1 more source

Suspended Tissue Open Microfluidic Patterning (STOMP)

open access: yesAdvanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack   +22 more
wiley   +1 more source

How we treat bleeding associated with direct oral anticoagulants [PDF]

open access: yes, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo   +4 more
core   +1 more source

Perovskite‐Graphene Heterostructure Biosensor Integrated with Biotunable Nanoplasmonic Ternary Logic Gate for Ultrasensitive Cytokine Detection

open access: yesAdvanced Science, EarlyView.
This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun   +7 more
wiley   +1 more source

Characterizing plasmin-induced lag phase and application of PDMS microfluidics to detection of fibrinolytic activity [PDF]

open access: yes, 2018
Physical trauma is responsible for over six million deaths annually, and of these roughly 40 percent result from acute traumatic coagulopathy (ATC) occurring in the first few hours of incidence. Patients who have developed ATC have significantly improved
Ghani, Naveed
core  

Method of treating endothelial dysfunction comprising administration of a thrombin peptide derivative [PDF]

open access: yes, 2012
Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.Board of Regents, University of ...
Carney, Darrell H.   +2 more
core   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

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