Results 211 to 220 of about 249,410 (353)

The use of sequence-specific antibodies to identify a secondary binding site in thrombin.

, 1988
G. Noé, Jan Hofsteenge, G Rovelli, Stuart R. Stone   +3 more
openalex   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Inhibition of the JAK and MEK Pathways Limits Mitochondrial ROS Production in Human Saphenous Vein Smooth Muscle Cells. [PDF]

Cells
Bolanle IO, Hobkirk JP, Loubani M, Sturmey RG, Palmer TM.   +4 more
europepmc   +1 more source

Effect Of An Inhibitor Of Thromboxane Synthesis (UK-37, 248-01) On Thrombin Induced Pulmonary Insufficiency In The Rat [PDF]

, 1981
Håkan Sandler, Tom Saldeen
openalex   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Fluoroscopy-guided balloon blocking combined with thrombin injection for pseudoaneurysm of the common femoral artery. [PDF]

Medicine (Baltimore)
Liu Z, Xia Y, Kong J, Gu J, Xia M.
europepmc   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Heart‐On‐a‐Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell‐ and Tissue‐Scale Contractile Stresses

Small, EarlyView.
We present a heart‐on‐a‐chip platform embedded with ultrasoft mechanosensors for real‐time, multi‐scale stress mapping in engineered cardiac tissues. The system enables simultaneous quantification of local cell‐generated stresses and global tissue contractile forces.
Ali Mousavi, Christina‐Marie Boghdady, Shihao Cui, Sabra Rostami, Amid Shakeri, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Milica Radisic, Christopher Moraes, Houman Savoji   +10 more
wiley   +1 more source

Neutrophil Extracellular Traps Promote Platelet-Driven Contraction of Inflammatory Blood Clots via Local Generation of Endogenous Thrombin and Softening of the Fibrin Network. [PDF]

Cells
Saliakhutdinova SM, Khismatullin RR, Khabirova AI, Litvinov RI, Weisel JW.   +4 more
europepmc   +1 more source

Normal thrombin generation in neonates in spite of prolonged conventional coagulation tests

, 2008
Armando Tripodi, Luca A. Ramenghi, V. Chantarangkul, Agnese De Carli, Marigrazia Clerici, Michela Groppo, Fabio Mosca, Pier Mannuccio Mannucci   +7 more
openalex   +2 more sources