Results 271 to 280 of about 241,744 (291)

Controlled Nanoconfinement in a Microfluidic Modular Bead Array Device via Elastomeric Diaphragm Collapse for Enhancing Biomolecular Binding Kinetics

open access: yesSmall, EarlyView.
A modular platform for controlled nanoconfinement over a large area is presented using an elastomeric diaphragm integrated with strain sensors and microfabricated posts (≈500 nm) to enhance biomolecular binding by alternating between confinement and bulk transport for rapid DNA immobilization and screening aptamers on their binding affinities to target
Abdullah‐Bin Siddique   +4 more
wiley   +1 more source

Nucleic Acid‐Modified Nanoparticles for Cancer Therapeutic Applications

open access: yesSmall, EarlyView.
Nucleic acid‐modified nanoparticles act as functional hybrids for chemodynamic, photodynamic, photothermal, and gene therapy of cancer cells. These are exemplified with aptamer‐modified catalytic nanoparticles, photosensitizer‐oligonucleotide functionalized nanoparticles, drug‐loaded stimuli‐responsive nucleic acid‐caged nanoparticle carriers, and ...
Yunlong Qin   +2 more
wiley   +1 more source

Functional and Structural Analyses of Diverse G‐Quadruplex and Non‐G‐Quadruplex Structures Formed by Guanine‐Rich Nucleic Acids: A Study on the Insulin Aptamer

open access: yesSmall, EarlyView.
IGA3, a guanine‐rich insulin aptamer, adopts different structures depending on environmental conditions. Under low cation concentrations, IGA3 forms a non‐G‐quadruplex structure that interacts with insulin. This finding highlights that guanine‐rich nucleic acids, in structures other than G‐quadruplex, can also bind to proteins, revealing valuable ...
Naoya Iwano   +9 more
wiley   +1 more source

Reversible High-Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation. [PDF]

open access: yesAdv Sci (Weinh)
Shi C   +9 more
europepmc   +1 more source

Hemostasis in orthotopic liver transplantation [PDF]

open access: yes, 1993
Blombäck, M.   +10 more
core  

Fabricating Microfluidic Co‐Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell‐Derived Adipose Tissue

open access: yesSmall, EarlyView.
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy   +2 more
wiley   +1 more source

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