Results 271 to 280 of about 241,744 (291)
Targeting PAR1 activation in JAK2V617F-driven philadelphia-negative myeloproliferative neoplasms: Unraveling its role in thrombosis and disease progression. [PDF]
Uslu-Biçak İ, Nalçaci M, Sözer S.
europepmc +1 more source
A modular platform for controlled nanoconfinement over a large area is presented using an elastomeric diaphragm integrated with strain sensors and microfabricated posts (≈500 nm) to enhance biomolecular binding by alternating between confinement and bulk transport for rapid DNA immobilization and screening aptamers on their binding affinities to target
Abdullah‐Bin Siddique+4 more
wiley +1 more source
Successful Management of Acute Obscure Gastrointestinal Bleeding (OGIB) Using Long Tube-Directed Hemostasis: A Case Report. [PDF]
Zhang J, Hsieh Y, Xu J.
europepmc +1 more source
Nucleic Acid‐Modified Nanoparticles for Cancer Therapeutic Applications
Nucleic acid‐modified nanoparticles act as functional hybrids for chemodynamic, photodynamic, photothermal, and gene therapy of cancer cells. These are exemplified with aptamer‐modified catalytic nanoparticles, photosensitizer‐oligonucleotide functionalized nanoparticles, drug‐loaded stimuli‐responsive nucleic acid‐caged nanoparticle carriers, and ...
Yunlong Qin+2 more
wiley +1 more source
IL-6 as a Mediator of Platelet Hyper-Responsiveness. [PDF]
Webb CE, Vautrinot J, Hers I.
europepmc +1 more source
IGA3, a guanine‐rich insulin aptamer, adopts different structures depending on environmental conditions. Under low cation concentrations, IGA3 forms a non‐G‐quadruplex structure that interacts with insulin. This finding highlights that guanine‐rich nucleic acids, in structures other than G‐quadruplex, can also bind to proteins, revealing valuable ...
Naoya Iwano+9 more
wiley +1 more source
Reversible High-Affinity Binding of Coagulation Factor Xa to Zeolites Induces Accelerated Blood Coagulation. [PDF]
Shi C+9 more
europepmc +1 more source
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy+2 more
wiley +1 more source
Risk of First Venous Thrombosis by Comparing Different Thrombin Generation Assay Conditions: Results from the MEGA Case-control Study. [PDF]
Winckers K+6 more
europepmc +1 more source