Results 311 to 320 of about 100,897 (348)
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Thrombin generation in ankylosing spondylitis
Clinical Rheumatology, 2010Ankylosing spondylitis (AS) is a chronic inflammatory disease associated with an increase in cardiovascular risk. Thrombin generation is associated with the risk of thrombosis, and the endogenous thrombin potential (ETP) has been proposed as a parameter for plasma-based hypercoagulability.
Clément, Prati +3 more
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Thrombin generation after physical exercise
Thrombosis Research, 1993Many investigators have studied the influence of physical exercise on hemostatic system and it is well accepted that exercise causes an activation of coagulation as indicated by a shortening of aPTT and by an increase in plasma factor VIII activity and levels.
PRISCO, DOMENICO +6 more
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Thrombin generation in antiphospholipid syndrome
Lupus, 2012Our objective was to study acquired Activated Protein C (APC) resistance in patients with antiphospholipid antibodies (aPL) using a thrombin generation based assay. We compared patients with and without lupus (systemic lupus erythematosus, SLE). A parameter summarizing APC inhibition of thrombin generation with increasing APC concentrations (IC50-APC)
S, Zuily +5 more
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Thrombin generation in clinical conditions
Thrombosis Research, 2012Commercial assays for determining thrombin generation in plasma are being tested in clinical conditions associated with thrombosis or bleeding. While pre-analytical conditions remain a source of inter laboratory variation, demanding for further standardization, clinical research proceeds. In patients at risk of venous thrombosis thrombin generation (TG)
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Intravascular contrast media and thrombin generation
Acta Radiologica, 1994This study focuses on the effect of contrast media (CM) on thrombin generation. In vitro studies consisted of incubating nonanticoagulated whole blood with ionic CM (sodium meglumine diatrizoate, ioxaglate), nonionic CM (iohexol, iopamidol) or glucose in plastic tubes.
Z, Parvez, H, Vik
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Thrombin Generation in Zebrafish
Blood, 2014Abstract Introduction Recently, the whole blood calibrated automated thrombogram (CAT) was miniaturized enabling the measurement of thrombin generation (TG) in a limited volume (5 µl) of whole blood. Consequently, this approach may be used to determine TG in small lab animals.
Evelien Schurgers +4 more
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Markers of increased thrombin generation
La Ricerca in Clinica e in Laboratorio, 1990Blood clotting activation causes an increased thrombin generation. The direct measurement of plasma thrombin is not feasible due to the absence of reliable methods. Thus, only indirect approaches are possible. Different markers of thrombin generation have been proposed in the past years. Some methods are nowadays of historical interest.
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Thrombin generation and venous thromboembolism
Hämostaseologie, 2008SummaryVenous thromboembolism is a chronic and potential fatal disease. Determination of recurrence risk is time-consuming and costly, and sometimes not feasible: many patients carry more than one risk factor, the relevance of some factors with regard to risk of recurrence is unknown, and existence of thus far unknown risk factors must be considered. A
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Thrombin Generation in Pregnancy
2008A well functioning hemostasis depends on the well-balanced interaction between many procoagulatory and inhibiting factors of the coagulation and the fibrinolytic system. During normal pregnancy this balance is shifted towards a state of hypercoagulability [1], which is more marked around term and in the immediate post partum period [2].
A. Rosenkranz +7 more
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2023
ที่มาและความสำคัญ : ผู้ป่วยมะเร็งทางโลหิตวิทยาพบความผิดปกติของการกระตุ้นการแข็งตัวของเลือดได้บ่อย ทำให้เกิดปัญหาเลือดออกง่ายผิดปกติ หรือเลือดแข็งตัวผิดปกติ ซึ่งอาจเกิดจากการกระตุ้นปัจจัยการแข็งตัวของเลือดที่ผิดปกติจากเซลล์มะเร็งเอง หรือเกิดจากการรักษาโดยยาเคมีบำบัด ซึ่งจากความผิดปกติดังกล่าวอาจเป็นสาเหตุของภาวะแทรกซ้อนต่างๆในผู้ป่วยมะเร็งเม็ดเลือดขาวเฉี
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ที่มาและความสำคัญ : ผู้ป่วยมะเร็งทางโลหิตวิทยาพบความผิดปกติของการกระตุ้นการแข็งตัวของเลือดได้บ่อย ทำให้เกิดปัญหาเลือดออกง่ายผิดปกติ หรือเลือดแข็งตัวผิดปกติ ซึ่งอาจเกิดจากการกระตุ้นปัจจัยการแข็งตัวของเลือดที่ผิดปกติจากเซลล์มะเร็งเอง หรือเกิดจากการรักษาโดยยาเคมีบำบัด ซึ่งจากความผิดปกติดังกล่าวอาจเป็นสาเหตุของภาวะแทรกซ้อนต่างๆในผู้ป่วยมะเร็งเม็ดเลือดขาวเฉี
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