Results 321 to 330 of about 100,897 (348)

Thrombin Generation in Acute Myeloblastic Leukemia

1990
Bleeding complications are responsible for 10%–30% of early deaths in acute leukemia [1]. Despite appropriate supportive care, including prophylactic platelet transfusion therapy, this rate has remained almost unchanged [2]. In addition to disease-related or chemotherapy-induced severe thrombocytopenia and platelet dysfunction, disorders of coagulation
R E, Scharf, U, Stoffels, W, Schneider
openaire   +2 more sources

Thrombin Generation in Children

2007
Newborns and children have lower concentrations of coagulation factors and inhibitors than adults. The range of thrombin concentration varies from 20 % for premature newborns and 35 % for newborns to 80 % in children [1] resulting in a lower thrombin generation (TG). But TG not only depends on age. Also patients with hemophilia A and B show a lower TG [
A. Siegemund, S. Horneff, R. Schobess
openaire   +1 more source

Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion

Signal Transduction and Targeted Therapy, 2022
Yang Shu, Yu-Jie Guo, Scott Ayton
exaly  

Combination of tumour-infarction therapy and chemotherapy via the co-delivery of doxorubicin and thrombin encapsulated in tumour-targeted nanoparticles

Nature Biomedical Engineering, 2020
Suping Li, Yinlong Zhang, Shih-Hsin Ho
exaly  

Thrombin is a therapeutic target for non-small-cell lung cancer to inhibit vasculogenic mimicry formation

Signal Transduction and Targeted Therapy, 2020
Bing Zhao, Yanling Zhanng, Wei Mo
exaly  

[Thrombinoscopy: measuring thrombin generation].

Nederlands tijdschrift voor geneeskunde, 2011
A test is needed of which the score is low in case of haemorrhagic tendency and high in case of thrombotic tendency. Emerging evidence shows that thrombin generation is a promising candidate. Recently it became possible to measure the course in thrombin concentration in clotting blood or blood plasma in an simple way suitable for application in a ...
openaire   +1 more source

Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation

Nature Medicine, 2002
Lidija Covic, Athan Kuliopulos
exaly  

Thrombin Generation Assays

2019
Mikhail Roshal, Morayma Reyes Gil
openaire   +1 more source

Dabigatran etexilate – a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity

Thrombosis and Haemostasis, 2010
Andreas Clemens
exaly  

Aptamer-Functionalized Au Nanoparticles for the Amplified Optical Detection of Thrombin

Journal of the American Chemical Society, 2004
Valeri Pavlov, Yi Xiao, Itamar Willner
exaly