Results 121 to 130 of about 3,126,313 (204)

Crosstalk between Oxidative Stress, Chronic Inflammation and Disease Progression in Essential Thrombocythemia

Revista de Chimie, 2019
Essential thrombocythemia (ET) is a Philadelphia-negative chronic myeloproliferative neoplasm characterized by acquired somatic mutations: JAK2, CALR or MPL.
A. Găman, C. Moisă, C. Diaconu, M. Găman   +3 more
semanticscholar   +1 more source

BCR/ABL positive thrombocythemia: a diagnostic dilemma

The Egyptian Journal of Internal Medicine, 2017
Both chronic myeloid leukemia and essential thrombocythemia are part of the spectrum of myeloproliferative neoplasm. Therefore, considerable overlap may occur in the clinical manifestations, and hematological and molecular findings in some patients.
Lubna Zafar, Feroz Alam, Anjum Parvez, Srikant Behera   +3 more
doaj   +1 more source

Population pharmacokinetics of fedratinib in patients with myelofibrosis, polycythemia vera, and essential thrombocythemia

Cancer Chemotherapy and Pharmacology, 2019
Fedratinib (SAR302503, TG101348) is an orally administered Janus kinase (JAK) 2-selective inhibitor that is being developed for the treatment of patients with myelofibrosis (MF).
K. Ogasawara, S. Zhou, G. Krishna, M. Palmisano, Yan Li   +4 more
semanticscholar   +1 more source

Komplex molekuláris genetikai vizsgálati algoritmus myeloproliferativ neoplasiák diagnosztikájában [PDF]

, 2015
Introduction: Mutations in Janus kinase 2, calreticulin and thrombopoietin receptor genes have been identified in the genetic background of Philadelphia chromosome negative, "classic" myeloproliferative neoplasms.
Andrikovics, Hajnalka, Balassa K, Bors, András, Bátai A, Csomor, Judit, Egyed M, Fekete S, Halm G, Krähling T, Masszi, Tamás, Meggyesi N, Reményi P, Tordai, Attila   +12 more
core   +1 more source

Essential thrombocythemia presenting as digital ischemia

Bangabandhu Sheikh Mujib Medical University Journal, 2017
Essential thrombocythemia is a myeloproliferative disease and is characterized by increased production of platelet and increased megakaryocytes in the bone marrow.
Md. Nazmul Hasan, Md. Abdur Rahim, Quazi Mamtaz Uddin Ahmed, Md. Syedul Islam, Md. Atikur Rahman, Md. Shamim   +5 more
doaj   +1 more source

Non ST-segment elevation myocardial infarction in patient with essential thrombocythemia

Thrombosis Journal, 2009
A 68-year-old woman presented with acute chest pain and a greatly increased platelet count. Cardiac catheterization revealed subtotal occlusion and a thrombus-like filling defect in the right coronary artery.
Tengiz Istemihan, Saygi Serkan, Kosova Buket, Sahin Fahri, Tuzun Nurullah, Alioglu Emin, Turk Ugur, Ozsan Nazan, Ercan Ertugrul   +8 more
doaj   +1 more source

Enhanced platelet adhesion in essential thrombocythemia after in vitro activation [PDF]

, 2010
Objective: Essential thrombocythemia (ET) is a chronic myeloproliferative disorder characterized by elevated platelet counts and increased risk of thrombosis.
Andreas C. Eriksson, Kourosh Lotfi, Per A. Whiss   +2 more
core  

Estudio molecular en Neoplasias Mieloproliferativas Crónicas: mutación JAK2V617F [PDF]

, 2013
La mutación JAK2V617F constituye la alteración molecular más frecuente en Neoplasias Mieloproliferativas Crónicas BCR-ABL-negativas, detectándose en > 95% de los pacientes con Policitemia Vera y alrededor de 50-60% de aquellos con Mielofibrosis Primaria ...
Heller, Paula Graciela, Lev, Paola Roxana   +1 more
core   +1 more source

Chilblains as a Clue for the Diagnosis of Essential Thrombocythemia

Acta Médica Portuguesa
N ...
Hugo J. Leme, José Ramos, Ângela Roda
doaj   +1 more source

Influència de l'haplotip 46/1 del gen JAK2 en la variació de la càrrega al·lèlica de la mutació JAK2V617F en pacients amb policitèmia vera i trombocitèmia esencial [PDF]

, 2012
La presència de l'haplotip 46/1 del gen JAK2 predisposa a neoplàsies mieloproliferatives associades a la mutació de JAK2V617F, però la seva rellevància clínica és desconeguda.
Angona i Figueras, Anna, Besses i Raebel, Carles, Universitat Autònoma de Barcelona. Departament de Medicina, Universitat Autònoma de Barcelona. Facultat de Medicina   +3 more
core