Results 41 to 50 of about 21,464 (182)

Methylation of SOCS3 in Myeloproliferative Neoplasms and Secondary Erythrocytosis/Thrombocythemia

Turkish Journal of Hematology, 2013
OBJECTIVE: Myeloproliferative neoplasms (MPNs) like essential thrombocythemia (ET), polycythemia vera (PV), and primary myelofibrosis (PMF) are acquired clonal hematopoietic stem cell disorders and originate from a multipotent hematopoietic stem cell ...
Deniz Torun, Oral Nevruz, Mesut Akyol, Salih Kozan, Muhterem Bahçe, Şefik Güran, Cengiz Beyan   +6 more
doaj   +1 more source

Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations

Haematologica, 2014
Somatic insertions/deletions in the calreticulin gene have recently been discovered to be causative alterations in myeloproliferative neoplasms. A combination of qualitative and quantitative allele-specific polymerase chain reaction, fragment-sizing ...
Hajnalka Andrikovics, Tunde Krahling, Katalin Balassa, Gabriella Halm, Andras Bors, Magdalena Koszarska, Arpad Batai, Janos Dolgos, Judit Csomor, Miklos Egyed, Andrea Sipos, Peter Remenyi, Attila Tordai, Tamas Masszi   +13 more
doaj   +1 more source

Multiple cardiac surgical procedures in a case of an octogenarian with essential thrombocythemia [PDF]

, 2023
Motohiro Maeda, Shun‐ichiro Sakamoto, Tomohiro Murata, Atsushi Hiromoto, Kenji Suzuki, Yôsuke Ishii   +5 more
openalex   +1 more source

Rituximab and Intravenous Immunoglobulin (IVIG) for Refractory Eosinophilic Fasciitis: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Eosinophilic fasciitis (EF) is a rare condition with an unknown cause. This case study showed that a 40‐year‐old man with EF did not respond to standard treatments but improved after receiving rituximab and intravenous immunoglobulin (IVIG). Further studies are needed to confirm rituximab's effectiveness and long‐term safety for EF.
Maryam Sahebari, Motahhareh Karimoddini, Naser Tayyebi Meibodi, Sajad Ataei Azimi, Shadan Tafreshian   +4 more
wiley   +1 more source

Risk Factors for Thrombosis in Essential Thrombocythemia: A Clinico-Pathological Study of 138 Patents in a Middle Eastern Population [PDF]

, 2023
Aamer Aleem, Abdullah Alqahtani, Leena Alshaman, Nawaf Aldawsari, Farjah Algahtani, Ahmed Jamal, Zafar Iqbal, Musa Alzahrani, Khalid Alsaleh, Sarah Sewaralthahab, Fatimah Alshalati, Naif Saud Albudayri, Ghazi Alotaibi   +12 more
openalex   +1 more source

Evidence for a founder effect of the MPL-S505N mutation in eight Italian pedigrees with hereditary thrombocythemia

Haematologica, 2009
Background Hereditary thrombocythemia is a rare disease characterized by increased megakaryopoiesis and overproduction of platelets. Germ line mutations have been identified in the genes for thrombopoietin (THPO) and its receptor, MPL.
Kun Liu, Maurizio Martini, Bianca Rocca, Christopher I. Amos, Luciana Teofili, Fiorina Giona, Jianmin Ding, Hirokazu Komatsu, Luigi M. Larocca, Radek C. Skoda   +9 more
doaj   +1 more source

The Immunological Consequences of Clonal Hematopoiesis in Heart Failure

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Inflammation is increasingly recognized as a central driver of heart failure (HF), particularly in older adults, yet the underlying immune mechanisms remain diverse and incompletely understood. Clonal hematopoiesis (CH), defined by the expansion of somatically mutated hematopoietic clones, has emerged as a risk factor for the development of ...
Megan A. Evans, Kenneth Walsh
wiley   +1 more source

Essential thrombocythemia and acute myocardial infarction treated with rescue coronary angioplasty

Arquivos Brasileiros de Cardiologia, 1999
A 48-year-old man with essential thrombocythemia suffered an extensive anterior acute myocardial infarction; this is a rare association. A pharmacological thrombolysis was performed, without success.
Antonio Esteves Fº, Francisco de Assis Costa, Antonio Augusto Guimarães Lima, Luiz Junya Kajita, Eulógio Emílio Martinez Fº   +4 more
doaj   +1 more source

The JAK2V617F and CALR mutations and risk of cancer, cardiovascular diseases, and all‐cause mortality

Journal of Internal Medicine, Volume 299, Issue 1, Page 79-94, January 2026.
Abstract Background Clonal hematopoiesis (CH) is associated with adverse outcomes. We hypothesized that CH (JAK2V617F and CALR) is associated with cancer, vascular disease, and all‐cause mortality, even at a variant allele frequency (VAF) <1%. Methods We screened 19,832 individuals from the Danish General Suburban Population Study for JAK2V617F and ...
Morten Kranker Larsen, Vibe Skov, Lasse Kjær, Christina Schjellerup Eickhardt‐Dalbøge, Trine Alma Knudsen, Marie Hvelplund Kristiansen, Anders Lindholm Sørensen, Sabrina Cordua, Troels Wienecke, Mette Grymer Jensen, Morten Andersen, Johnny T. Ottesen, Johanne Gudmand‐Høyer, Jordan Andrew Snyder, Henrik Enghusen Poulsen, Thomas Stiehl, Christina Ellervik, Hans Carl Hasselbalch   +17 more
wiley   +1 more source

Early recognition of intraventricular hemorrhage in the setting of thrombocytosis in the emergency department

Open Access Emergency Medicine, 2016
Marvinia Charles, Romy Fontoura, Gregory Sugalski Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA Abstract: Thrombocytosis is frequently encountered as an incidental laboratory finding since isolated thrombocytosis ...
Charles M, Fontoura R, Sugalski G
doaj