Results 101 to 110 of about 288,284 (303)

A Universal and Versatile Zwitterionic Coating for Blood‐Contacting Catheters with Long Lengths and Complex Geometries

open access: yesAdvanced Science, EarlyView.
A universal and versatile zwitterion coating strategy is developed for blood‐contacting catheters with long lengths and complex geometries. The coating exhibits near‐zero fouling, superior anticoagulation, and selective biocapturing properties while maintaining excellent stability under dynamic blood flow.
Tong Zhang   +6 more
wiley   +1 more source

Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy

open access: yesHepatology, EarlyView., 2022
Serum bile acid levels predict outcomes in patients with biliary atresia who achieve normalized bilirubin levels after Kasai portoenterostomy. Abstract Background and Aims In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP).
Sanjiv Harpavat   +22 more
wiley   +1 more source

Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.

open access: yesNew England Journal of Medicine, 1995
BACKGROUND Heparin-induced thrombocytopenia, defined by the presence of heparin-dependent IgG antibodies, typically occurs five or more days after the start of heparin therapy and can be complicated by thrombotic events.
T. Warkentin   +6 more
semanticscholar   +1 more source

Severe Fever with Thrombocytopenia Syndrome, Japan, 2013–2017

open access: yesEmerging Infectious Diseases, 2020
We conducted an epidemiologic study of severe fever with thrombocytopenia syndrome (SFTS) in Japan during 2013–2017. Of 303 cases reported during that period, 133 (44%) were included in this study.
Yusuke Kobayashi   +11 more
semanticscholar   +1 more source

Isatuximab plus carfilzomib and dexamethasone versus carfilzomib and dexamethasone in elderly patients with relapsed multiple myeloma: IKEMA subgroup analysis

open access: yesHematological Oncology, Volume 40, Issue 5, Page 1020-1029, December 2022., 2022
Abstract In this subgroup analysis of the randomized, Phase 3 IKEMA study (NCT03275285), we evaluated efficacy and safety of the anti‐CD38 monoclonal antibody isatuximab (Isa) in combination with carfilzomib‐dexamethasone (Isa‐Kd) versus Kd in older (≥70 years of age, n = 86) and younger (<70 years, n = 216) patients with relapsed multiple myeloma (MM).
Thierry Facon   +15 more
wiley   +1 more source

Impact of gastrectomy on efficacy and safety of second‐line chemotherapy patients with advanced gastric cancer: Exploratory analysis of two randomized phase III trials

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In an analysis of two RCTs of IRI‐based second‐line chemotherapy for AGC, patients with prior gastrectomy had better OS and PFS than patients without prior gastrectomy. Furthermore, patients with prior gastrectomy had a better prognosis in OS and PFS adjusted for background factors as well. Abstract Aims Second‐line chemotherapy (SLC) improves survival
Kazuhiro Nishikawa   +12 more
wiley   +1 more source

Juvenile mucopolysaccharidosis plus disease caused by a missense mutation in VPS33A

open access: yesHuman Mutation, Volume 43, Issue 12, Page 2265-2278, December 2022., 2022
Abstract A rare and fatal disease resembling mucopolysaccharidosis in infants, is caused by impaired intracellular endocytic trafficking due to deficiency of core components of the intracellular membrane‐tethering protein complexes, HOPS, and CORVET. Whole exome sequencing identified a novel VPS33A mutation in a patient suffering from a variant form of
Elena V. Pavlova   +11 more
wiley   +1 more source

Practical guidance for the management of adults with immune thrombocytopenia during the COVID‐19 pandemic

open access: yesBritish Journal of Haematology, 2020
This document aims to provide practical guidance for the assessment and management of patients with thrombocytopenia, with a particular focus on immune thrombocytopenia (ITP), during the COVID‐19 pandemic.
S. Pavord   +10 more
semanticscholar   +1 more source

Vancomycin-Induced Thrombocytopenia as a Less Considered Contributing Cause in Differential Diagnosis of Thrombocytopenia: A Case Report

open access: yesJournal of Pharmaceutical Care, 2019
Thrombocytopenia has been reported as an adverse effect of numerous medicines including vancomycin. Due to contribution of other suspected causes and lack of a standard diagnostic test, vancomycin-induced thrombocytopenia has been less addressed in ...
Sholeh Ebrahimpour   +2 more
doaj  

Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)

open access: yesJournal of Clinical Medicine, 2017
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated and/or T cell-mediated platelet destruction are key processes.
A. Zufferey, R. Kapur, J. Semple
semanticscholar   +1 more source

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