Results 101 to 110 of about 432,090 (383)

Human Cytomegalovirus: detection of congenital and perinatal infection in Argentina [PDF]

, 2004
BACKGROUND: Human cytomegalovirus (CMV) is one of the most commonly found agents of congenital infections. Primary maternal infection is associated with risk of symptomatic congenital diseases, and high morbidity is frequently associated with very low ...
Alicia Alonso, Angélica Lidia Distéfano, B Zweygberg Wirgart, D Shibata, DJ Morris, E Gonczol, Fabián Martin, Fabián Pardon, GJ Demmler, J Darlington, JC Mendez, JR Murph, KB Fowler, M Barbi, M Barbi, M Brytting, M Shibata, MG Revello, MG Revello, NM Jiwa, PD Griffiths, PV Coyle, RJ Whitley, S Chou, SA Plotkin, SB Boppana   +25 more
core   +3 more sources

COVID‐19‐associated immune thrombocytopenia

British Journal of Haematology, 2020
Thrombocytopenia is a risk factor for increased morbidity and mortality in patients with the new severe acute respiratory syndrome corona virus, SARS-CoV-2 infection (COVID-19 infection).1 Thrombocytopenia in COVID-19 patients may be caused by ...
G. Bomhof, P. Mutsaers, F. Leebeek, Peter A. W. Boekhorst, J. Hofland, F. N. Croles, A. G. Jansen   +6 more
semanticscholar   +1 more source

Platelet Activation Mechanisms and Consequences of Immune Thrombocytopenia

Cells, 2021
Autoimmune disorders are often associated with low platelet count or thrombocytopenia. In immune-induced thrombocytopenia (IIT), a common mechanism is increased platelet activity, which can have an increased risk of thrombosis.
Siyu Sun, R. Urbanus, H. ten Cate, P. D. de Groot, B. de Laat, J. Heemskerk, M. Roest   +6 more
semanticscholar   +1 more source

Autoimmune Hemolytic Anemia and Immune Thrombocytopenia: A Unique Presentation of Kawasaki Disease [PDF]

, 2021
Chloe Kupelian, Bindu Kanathezhath Sathi, Deepika Singh   +2 more
openalex   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Neutrophil activation and NETosis are the major drivers of thrombosis in heparin-induced thrombocytopenia

Nature Communications, 2019
Heparin-induced thrombocytopenia/thrombosis (HIT) is a serious immune reaction to heparins, characterized by thrombocytopenia and often severe thrombosis with high morbidity and mortality. HIT is mediated by IgG antibodies against heparin/platelet factor
J. Perdomo, Halina Leung, Z. Ahmadi, Feng Yan, James J. H. Chong, F. Passam, B. Chong   +6 more
semanticscholar   +1 more source

Inherited thrombocytopenias

Hematology, 2015
No ...
Balduini, Carlo L, NORIS, PATRIZIA
openaire   +3 more sources

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Bevacizumab-induced immune thrombocytopenia in an ovarian cancer patient with mixed connective tissue disease: case report and literature review

Frontiers in Immunology
Drug-induced immune thrombocytopenia is an adverse reaction marked by accelerated destruction of blood platelets. In cancer therapy, thrombocytopenia has many other causes including bone marrow suppression induced by chemotherapeutic agents, infection ...
Yunting Zhang, Fanchun Yang, Jining Wang, Hui Fu, Fuming Shen, Jie Liu, Dongjie Li   +6 more
doaj   +1 more source

PATHOBIOLOGY AND TREATMENT OF HEPATITIS VIRUS-RELATED THROMBOCYTOPENIA

Mediterranean Journal of Hematology and Infectious Diseases, 2009
Thrombocytopenia is a well recognized complication of infections, including those from hepatotropic viruses. Thrombocytopenia may actually be the only manifestation of vital hepatitis, which should therefore be considered in the differential diagnosis of
Roberto Stasi, Lian Wea Chia, Pallavi Kalkur, Robert Lown, Muriel S. Shannon   +4 more
doaj   +1 more source