Results 171 to 180 of about 314,849 (336)

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

open access: yesInternational Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman   +15 more
wiley   +1 more source

Revisiting intraperitoneal chemotherapy for advanced high‐grade serous ovarian cancer

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare overall survival (OS) in patients with high‐grade serous ovarian cancer (HGSOC) treated with intraperitoneal (IP) chemotherapy versus intravenous (IV) chemotherapy. Methods A retrospective study of Stage III HGSOC with optimal primary cytoreduction during 2007–2019, followed by adjuvant IP or IV chemotherapy.
Joshua S Cheruvathur   +7 more
wiley   +1 more source

FIGO good practice recommendations: Assisted vaginal birth and the second stage of labor

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Cesarean birth (CB) rates are increasing globally, with a current prevalence of 21.1% and a projected prevalence of 28.5% by 2030. Conversely, assisted vaginal birth (AVB) rates are declining, with reported rates of less than 10% in low‐ and middle‐income countries (LMICs) and 10%–15% in high‐income countries (HICs). In some African countries,
Akaninyene E. Ubom   +11 more
wiley   +1 more source

Effect of Hemodialysis on Total and Free Lenvatinib Concentrations in a Patient With Metastatic Renal Cell Carcinoma

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Lenvatinib (LEN) concentrations in patients undergoing hemodialysis (HD) have not been examined. Herein, we report the effect of HD on total and free LEN concentrations in a patient with mRCC. Case Presentation The hemodialyzed patient was a 55‐year‐old Japanese male who was treated with 20 mg LEN daily.
Takahiro Ito   +5 more
wiley   +1 more source

Levamisol-induced thrombocytopenia. [PDF]

open access: bronze, 1977
A El-Ghobarey, H A Capell
openalex   +1 more source

Partial Splenic Embolization for Portal Hypertension Before Radical Nephrectomy in Renal Cell Carcinoma Patient: A Case Report

open access: yesIJU Case Reports, EarlyView.
ABSTRACT Introduction Partial splenic embolization is a valuable option to manage hypersplenism and reduce portal pressure while preserving splenic function. It may improve surgical safety in patients with portal hypertension. Case Presentation A 67‐year‐old Japanese male with renal cell carcinoma and hepatitis B‐related liver cirrhosis presented with ...
Shunsuke Watanabe   +6 more
wiley   +1 more source

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