Results 31 to 40 of about 432,090 (383)

Clinical Update of Severe Fever with Thrombocytopenia Syndrome

open access: yesViruses, 2021
Severe fever with thrombocytopenia syndrome (SFTS) is an acute febrile illness characterized by fever, leukopenia, thrombocytopenia, and gastrointestinal symptoms such as diarrhea, nausea, and vomiting resulting from infection with the SFTS virus (SFTSV).
Jun-Won Seo   +3 more
semanticscholar   +1 more source

Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy. [PDF]

open access: yes, 2016
Preclinical models suggest that histone deacetylase (HDAC) and mammalian target of rapamycin (mTOR) inhibitors have synergistic anticancer activity. We designed a phase I study to determine the safety, maximum tolerated dose (MTD), recommended phase II ...
Falchook, Gerald S.   +17 more
core   +2 more sources

Thrombocytopenia and its association with mortality in patients with COVID‐19

open access: yesJournal of Thrombosis and Haemostasis, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which causes novel coronavirus disease 2019 (COVID‐19), is spreading rapidly around the world. Thrombocytopenia in patients with COVID‐19 has not been fully studied.
Xiaobo Yang   +6 more
semanticscholar   +1 more source

Risk Factors and Outcome of Neonatal Thrombocytopenia

open access: yesJournal of Rawalpindi Medical College, 2020
Introduction: About 30% of neonates develop thrombocytopenia during hospital admission. Inevitable and irreversible complications can be prevented by determining the risk factors of neonatal thrombocytopenia. The present study was undertaken to determine
Hira Arif   +3 more
doaj   +1 more source

Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]

open access: yes, 2003
Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core   +1 more source

Mechanism of thrombocytopenia in COVID-19 patients

open access: yesAnnals of Hematology, 2020
Since December 2019, a novel coronavirus has spread throughout China and across the world, causing a continuous increase in confirmed cases within a short period of time.
Panyang Xu, Qi Zhou, Jiancheng Xu
semanticscholar   +1 more source

Thrombocytopenia in Young Patient due to Anti Tuberculosis Drugs : A Case Report

open access: yesJurnal Respirasi, 2020
Background: Most anti-tuberculosis (ATD) drugs are relatively safe, but unusual serious reactions can occur. Thrombocytopenia is an uncommon but potentially life-threatening complication of certain ATDs and is characterized by rapid destruction of ...
Aryani Prawita Sari   +1 more
doaj   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

open access: yes, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O.   +4 more
core   +2 more sources

Immune Thrombocytopenia [PDF]

open access: yesHematology, 2010
Immune thrombocytopenia (ITP) comprises a heterogeneous group of disorders characterized by autoimmune-mediated platelet destruction and impairment of thrombopoiesis. ITP may occur in the absence of an evident predisposing etiology (primary ITP) or secondary to a growing list of associated conditions (secondary ITP), and must be differentiated from ...
Adam, Cuker, Douglas B, Cines
openaire   +2 more sources

Hematological abnormalities beyond lymphocytosis during infectious mononucleosis: Epstein-Barr virus-induced thrombocytopenia

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2023
Background and aim: Thrombocytopenia in the course of Epstein-Barr virus mononucleosis is well-known; however, no recent series have investigated its frequency, associated factors, and evolution.
Arturo Gonzalez Quintela   +3 more
doaj   +1 more source

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