Results 221 to 230 of about 145,313 (292)

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve   +11 more
wiley   +1 more source

Updated evidence on epidemiology, diagnosis, and treatment for colonic diverticular bleeding

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Since 2020, multiple large‐scale studies (CODE BLUE‐J) in Japan have accelerated the accumulation of evidence on colonic diverticular bleeding (CDB). This review summarizes the latest findings regarding CDB epidemiology and endoscopic hemostasis.
Chikamasa Ichita   +6 more
wiley   +1 more source

Edoxaban‐induced enterocolitis: The first case report demonstrating distinct endoscopic and histological features

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Direct oral anticoagulants (DOACs), including edoxaban, are widely used for stroke prevention in atrial fibrillation and venous thromboembolism. While gastrointestinal bleeding and diarrhea are recognized adverse effects, DOAC‐induced enterocolitis has not been established as a distinct clinical entity.
Katsuya Endo   +8 more
wiley   +1 more source

The Risk of Colonoscopy‐related Bleeding in Patients With or Without Continued Treatment With an Antithrombotic Agent

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives We prospectively investigated the risk of colonoscopy‐related bleeding in relation to antithrombotic treatment. Methods This prospective, observational, single‐center cohort study (NCT02594813) enrolled consecutive patients who underwent colonoscopy, including the removal of colorectal polyps, regardless of the continuation of ...
Emi Nonaka   +5 more
wiley   +1 more source

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