Results 91 to 100 of about 141,128 (314)

Using Tenecteplase for Acute Ischemic Stroke: What Is the Hold Up? [PDF]

, 2020
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic medication for acute ischemic stroke. However, multiple recent studies comparing tenecteplase and alteplase suggest that tenecteplase is at least as efficacious as ...
Ataya, Ramsey, Brea, Isabel, Zitek, Tony
core  

Treatment of Coronary Bifurcation Stenoses Using the DK Mini Crush Technique—Analysis of Resources and Technical Success

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The DK‐mini‐Crush (DKMC) technique, an established strategy to treat coronary bifurcation stenoses, is known to be complex, with possible strain on time and resources. Aims To analyze predictors of technical failure as well as time and resourced required for each procedural step of th DKMC technique.
Florian Weidinger, Stephan Achenbach, Johannes Michael Altstidl, Merve Günes‐Altan, Maximilian Moshage, Monique Tröbs, Mohamed Marwan, Luise Gaede   +7 more
wiley   +1 more source

Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]

, 2018
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast, AD Michelson, B Labarthe, B Shen, C Patrono, CT Ammollo, D Capodanno, D Gailani, DA Gorog, Diana A. Gorog, DM Coenen, E Álvarez, ER Bates, F Kabirian, F Müller, F Semeraro, G Stephens, H Brogren, HE Speich, HE Speich, HJ Weiss, HJ Weiss, HR Baumgartner, J Zilberman-Rudenko, JD McFadyen, JI Weitz, JM Cosemans, JP Collet, JP Collet, K Hosokawa, K Nagatsuka, KS Sakariassen, L Valerio, LF Brass, M Cattaneo, M Farag, M Humbert, M Larsson, M Li, M Ungerer, MA Bailey, MI Furman, MJ Price, ML Montfoort von, MS Sabatine, P Andre, P Seizer, PA Borne von dem, PP Wadowski, R Hellmuth, R Nergiz-Unal, RA Ajjan, S Goto, S Goto, SA Shaya, SB Larsen, SJ Marciniak, T Heitzer, T Renné, VT Turitto, VT Turitto, WA Schumacher, WS Nesbitt, X Wang, Y Yano, YC Lau, ZM Ruggeri   +66 more
core   +2 more sources

Drug‐Coated Balloon‐Based Versus Drug‐Eluting Stent‐Only Treatment for Large Vessel Coronary Artery Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Drug‐coated balloon (DCB) treatment has shown outcomes comparable to drug‐eluting stent (DES) in small vessel coronary disease. However, evidence for its application in large vessel coronary artery disease (CAD) remains limited. Aims This study evaluated the clinical impact of DCB‐based percutaneous coronary intervention (PCI) in ...
Eun‐Seok Shin, Mi Hee Jang, Sunwon Kim, Dong Oh Kang, Ae‐Young Her, Chang‐Bae Sohn   +5 more
wiley   +1 more source

A cross sectional study on thrombolysis in ST elevation myocardial infarction and its assessment with respect to ST segment resolution and time delay [PDF]

Al Ameen Journal of Medical Sciences
Background: ST elevation myocardial infarction is a leading cause of death in India. Several socio-economic factors lead to delay in seeking thrombolysis. Aims and Objectives: To analyse the effect of time delay on the success of thrombolysis.
P.R. Bijeesh, Ahmed Altaf, Ruknuddin Sha, Ahmed Zahid   +3 more
doaj  

Effectiveness and Safety of Reduced‐Dose Prasugrel in an East Asian Population: PRASFIT‐ACS Emulation Using National Health Insurance Claims Data

Clinical Pharmacology &Therapeutics, EarlyView.
Prasugrel is recommended for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). However, East Asians exhibit a stronger antiplatelet response, raising concerns about bleeding risks with standard dosing. This retrospective cohort study evaluated the real‐world effectiveness and safety of reduced‐dose prasugrel in
Li‐Wen Huang, Yee‐Jen Wu, Fang‐Ju Lin, Chien‐Chih Wu, Hsin‐Yi Huang, Chi‐Chuan Wang, Xiaojuan Li   +6 more
wiley   +1 more source

Hospital volume and outcomes for acute pulmonary embolism: Multinational population based cohort study [PDF]

, 2019
[Objectives] To evaluate the association between experience in the management of acute pulmonary embolism, reflected by hospital case volume, and mortality.[Design] Multinational population based cohort study using data from the Registro Informatizado de
Bikdeli, Behnood, de Miguel-Diez, Javier, Jara-Palomares, Luis, Jimenez, David, Lobo, Jose Luis, Monreal, Manuel, Muriel, Alfonso, Quezada, Andres, RIETE investigators,, Ruiz-Artacho, Pedro, Yusen, Roger D   +10 more
core   +2 more sources

Centralising and optimising decentralised stroke care systems: a simulation study on short-term costs and effects

BMC Medical Research Methodology, 2017
Background Centralisation of thrombolysis may offer substantial benefits. The aim of this study was to assess short term costs and effects of centralisation of thrombolysis and optimised care in a decentralised system. Methods Using simulation modelling,
Maarten M. H. Lahr, Durk-Jouke van der Zee, Gert-Jan Luijckx, Patrick C. A. J. Vroomen, Erik Buskens   +4 more
doaj   +1 more source

The interaction between policy and education using stroke as an example [PDF]

, 2008
This paper discusses the interaction between healthcare policy at the European, UK and Scottish levels and the funding of education that underpins specific health policy priorities.
Aiken, Aiken, Alberts, Booth, Byford, Chapman, Chapman, Charlton, Corea, Demaerschalk, Duncan, Elkins, Fang, Glen, Glen, Hacke, Hoban, LaMonte, Langhorne, Levine, Lindley, Lorraine N. Smith, Louise E. Craig, Matchar, Sandercock, Shiell, Stone, Warlow, Warlow   +28 more
core   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source