Results 91 to 100 of about 193,589 (341)

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Clinical characteristics of unknown symptom onset stroke patients with and without diffusion-weighted imaging and fluid-attenuated inversion recovery mismatch [PDF]

, 2017
Background: Diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) mismatch was suggested to identify stroke patients with unknown time of symptom onset likely to be within the time window for thrombolysis. Aims: We aimed
Boutitie, Florent, Cheng, Bastian, Cho, Tae-Hee, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B., Fiehler, Jens, Ford, Ian, Galinovic, Ivana, Gerloff, Christian, Lemmens, Robin, Muir, Keith W., Nighoghossian, Norbert, Pedraza, Salvador, Puig, Josep, Roy, Pascal, Simonsen, Claus Z., Thijs, Vincent, Thomalla, Götz   +18 more
core   +2 more sources

Successful use of tPA for thrombolysis in COVID related ARDS: a case series

Journal of Thrombosis and Thrombolysis, 2020
We describe successful usage of low dose Tissue plasminogen activator (tPA) (30–50 mg) in three COVID19 critically ill patients, who were in worsening respiratory failure in-spite of being on therapeutic anticoagulation. All patients had respiratory rate 
A. Goyal, S. Saigal, Y. Niwariya, J. Sharma, Pooja Singh   +4 more
semanticscholar   +1 more source

Intravascular Ultrasound Findings Associated With Hydrodynamic Contrast Recanalization (HDR) of Coronary Chronic Total Occlusions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Hydrodynamic contrast recanalization (HDR) is a novel technique to facilitate wire crossing during chronic total occlusion (CTO) percutaneous coronary interventions (PCI). The mechanisms underlying HDR have not been fully described.
Salman A. Arain, Angelo Nascimbene, Akshitha Yarrabothula, Jaime Hudson, Emmanouil S. Brilakis, Antonio Colombo, Lorenzo Azzalini, M. Bilal Iqbal, Bernardo Cortese, Yukata Tadano, Tsutomu Fujita, Mauro Carlino, Biswajit Kar   +12 more
wiley   +1 more source

Investigating the effects of systemic thrombolysis on electrocardiography and pulmonary artery blood pressure in patients with pulmonary embolism

Health Science Reports
Background and Aims We aimed to evaluate the association between electrocardiography (ECG) and echocardiographic findings in patients with pulmonary embolism (PE) before and after systemic thrombolysis.
Mostafa Dastani, Vahid Reza Askari, Arya Nasimi Shad, Niyayesh Ghorbani, Vafa Baradaran Rahimi   +4 more
doaj   +1 more source

Diagnostic Ultrasound Induced Inertial Cavitation To Non-Invasively Restore Coronary And Microvascular Flow In Acute Myocardial Infarction [PDF]

, 2013
Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose of this study was to determine the type of cavitation required for success, and whether longer ...
Everbach, E. Carr, Feng, X., Gao, S., Liu, J., Lof, J., Porter, T. R., Powers, J., Radio, S., Shi, W., Unger, E., Vignon, F., Wu, J.   +11 more
core   +3 more sources

Prevalence and Prognostic Impact of Coronary Chronic Total Occlusions in Patients With Cardiogenic Shock

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mortality in patients with cardiogenic shock (CS) remains high despite advanced treatment strategies in CS patients, underlining the need for the identification of predictors of prognosis in CS patients. Therefore, the present study investigates the prognostic impact of coronary chronic total occlusions (CTO) in patients with CS ...
Michael Behnes, Moritz Schmidberger, Giuseppe Vadalà, Alice Moroni, Juan‐Luis Guiterrez‐Chico, Stylianos Pyxaras, Alexander Bufe, Florian Krötz, Kambis Mashayekhi, Mohamed Ayoub, Jonas Rusnak, Mohammad Abumayyaleh, Jonas Dudda, Kathrin Weidner, Ibrahim Akin, Tobias Schupp   +15 more
wiley   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Al, R.Y., Albers, G.W., Eyding, D., Furlan, A.J., Hacke, W.l, Lees, K.R., Rowley, H.A., Sachara, C., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Coronary Ectasia and ST Elevation Myocardial Infarction Patients: Does Atherosclerosis Influence Periprocedural Management and Long‐Term Prognosis?

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery ectasia (CAE) influences procedural outcomes in the context of ST‐elevation myocardial infarction (STEMI); however, its relationship with atherosclerotic coronary artery disease (ACAD) remains unclear. Aims This study aimed to compare clinical and procedural characteristics, as well as outcomes, in patients with ...
Victorine Fraichot, Jeanne Varlot, Florian Eggenspieler, Nassima Djaballah, Pierre Adrien Metzdorf, Edoardo Camenzind, Batric Popovic   +6 more
wiley   +1 more source

No space Left for Intravenous thrombolysis in acute stroke [PDF]

, 2016
Recent successful clinical trials of endovascular thrombectomy for large artery ischaemic stroke have established the value of this treatment modality as an adjunct to intravenous thrombolysis, not as an alternative: thrombectomy delivery was undertaken ...
Muir, Keith
core   +1 more source