Controversies in Thrombolysis [PDF]
Current Neurology and Neuroscience Reports, 2017 The purpose of the review is to examine recent evidence on the effects of intravenous thrombolysis and identify the remaining uncertainties.We review the results of two large trials (the third International Stroke Trial (IST-3) and The Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED)) and the publications from the individual ...
Sandercock, Peter, Ricci, Stefano
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Ultrasound and thrombolysis [PDF]
Vascular Medicine, 2001 Thrombolytic therapy and mechanical interventions are frequently used in the treatment of both arterial and venous thrombotic disease. Limitations to these approaches include failure to achieve reperfusion and complications including bleeding and vessel wall damage.
Charles W. Francis, Valentina Suchkova
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British Medical Bulletin, 2000 The most widely studied thrombolytic drugs in stroke have been streptokinase (SK) and alteplase. The three large trials with streptokinase were terminated prematurely. The combined results reveal an early increased risk of cerebral haemorrhage and death, with no net benefit at final follow-up, even in subgroups. Some controversy persists, however.
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Local Thrombolysis in High-Risk Pulmonary Embolism—13 Years Single-Center Experience
Clinical and Applied Thrombosis/Hemostasis, 2020 To evaluate the prognosis after local thrombolysis compared to systemic thrombolysis in high-risk pulmonary embolism. Observational study during 13 years which included 37 patients with high-risk pulmonary embolism treated with local thrombolysis and 36 ...
Liviu Macovei MD, PhD +7 more
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Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) [PDF]
, 2009 <p><b>Background and Purpose:</b> The optimal management of blood pressure (BP) in acute stroke remains unclear. For ischemic stroke treated with intravenous thrombolysis, current guidelines suggest pharmacological intervention if ...
Ahmed, N. +4 more
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Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]
, 2010 <p><b>Background and Purpose:</b> Thrombolysis for acute ischemic stroke in patients aged >80 years is not approved in some countries due to limited trial data in the very elderly.
Bluhmki, E. +4 more
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Медицинский вестник Юга России, 2015 Purpose: to evaluate the rate and severity of filtration renal dysfunction in patients with acute coronary syndrome after percutaneous coronary intervention (PCI) with X-ray contrast.Materials and Methods: serum creatinine levels were collected from 71 ...
N. T. Vatutin, M. I. Zinkovych
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An observational study of patient characteristics associated with the mode of admission to acute stroke services in North East, England [PDF]
, 2013 Objective Effective provision of urgent stroke care relies upon admission to hospital by emergency ambulance and may involve pre-hospital redirection.
Antony Bayer +37 more
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Outcome of Repeated Thrombolysis in Debrecen Thrombolysis Database [PDF]
Journal of Stroke and Cerebrovascular Diseases, 2017 Recombinant tissue plasminogen activator (rtPA) is an efficient therapy of acute ischemic stroke. The risk of a recurrent ischemic stroke is high. This prospective single center study aimed to assess whether or not the repeated rtPA treatment is beneficial for acute stroke patients.All thrombolysed patients' data at the Department of Neurology ...
Fekete, Klára +3 more
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