Results 201 to 210 of about 197,015 (348)
The prognosis prediction significance of Hounsfield unit value for stroke patients treated by intravenous thrombolysis [PDF]
, 2020 Zhengqi Zhu +6 more
openalex +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.This study provides a novel insight into the molecular mechanism whereby NBP protects mitochondria against ischemia/hypoxia damage, offering a promising drug for mitochondria‐targeting therapeutics for ischemic stroke. ABSTRACT Background Mitochondrial dysfunction is an initial event of the cascade reactions triggered by ischemic stroke, contributing ...
Haitao Zhang +7 more
wiley +1 more source
Mfsd2a‐Targeted Therapy for Ischemic Stroke: Mechanisms, Evidence, and Future Prospects
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.This graphical abstract illustrates the central role of Mfsd2a in maintaining blood–brain barrier (BBB) integrity under physiological conditions and its dysregulation following ischemic stroke. In the normal brain (left), Mfsd2a is highly expressed on brain microvascular endothelial cells (BMECs), where it inhibits caveolae‐mediated transcytosis and ...
Zhidong He, Jing Sun
wiley +1 more source
Cellular Communication Networks Mediated by Microglia in Ischemic Stroke
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.After ischemic stroke, microglia serve as central regulators within the neuroimmune network, engaging in dynamic crosstalk with neurons, astrocytes, vascular endothelial cells, and peripheral immune cells. By releasing cytokines, chemokines, extracellular vesicles, and transmitting mechanical signals, activated microglia coordinate inflammatory ...
Feiyu Ma +5 more
wiley +1 more source
Impact of abnormal glucose metabolism on the early neurological outcome in acute ischemic stroke patients treated with intravenous thrombolysis [PDF]
, 2022 Ling Wang +6 more
openalex +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.NBP promotes post‐stroke angiogenesis by upregulating VEGF through activation of the Akt/GSK3β pathway. NBP enhances vascular maturation via increased pericyte and astrocyte coverage of cerebral microvessels. NBP facilitates cerebral blood flow and augments cortical vasodilation in ischemic stroke mice.
Lan Zhang +10 more
wiley +1 more source